Mus musculus Gene: Fbxo25
Summary
InnateDB Gene IDBG-136117.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fbxo25
Gene Name F-box protein 25
Synonyms 9130015I06Rik; AI649137; Fbx25
Species Mus musculus
Ensembl Gene ENSMUSG00000038365
Encoded Proteins
F-box protein 25
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000147364:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:13907806-13940521
Strand Forward strand
Band A1.1
Transcripts
ENSMUST00000043520 ENSMUSP00000039544
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 110 interaction(s) predicted by orthology.
Predicted by orthology
Total 110 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
Biological Process
GO:0016567 protein ubiquitination
Cellular Component
GO:0005634 nucleus
GO:0019005 SCF ubiquitin ligase complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt Q9D2Y6
TrEMBL
UniProt Splice Variant
Entrez Gene 66822
UniGene Mm.396345
RefSeq NM_025785
OMIM
CCDS CCDS22118
HPRD
IMGT
MGI ID MGI:1914072
MGI Symbol Fbxo25
EMBL AK008027 AK018626 BC014749
GenPept AAH14749 BAB25418 BAB31315
RNA Seq Atlas 66822