Homo sapiens Gene: MRPL32
Summary
InnateDB Gene IDBG-13639.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MRPL32
Gene Name mitochondrial ribosomal protein L32
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000106591
Encoded Proteins
mitochondrial ribosomal protein L32
mitochondrial ribosomal protein L32
mitochondrial ribosomal protein L32
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L32 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome Xp. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:42932200-42948958
Strand Forward strand
Band p14.1
Transcripts
ENST00000223324 ENSP00000223324
ENST00000432845 ENSP00000415581
ENST00000413995 ENSP00000391562
ENST00000496564
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 30 experimentally validated interaction(s) in this database.
Experimentally validated
Total 30 [view]
Protein-Protein 29 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003735 structural constituent of ribosome
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005761 mitochondrial ribosome
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Organelle biogenesis and maintenance pathway
Mitochondrial translation pathway
Mitochondrial translation initiation pathway
Mitochondrial translation termination pathway
Mitochondrial translation elongation pathway
KEGG
Ribosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 64983
UniGene Hs.50252
RefSeq NM_031903
HUGO HGNC:14035
OMIM 611839
CCDS CCDS5468
HPRD 14752
IMGT
EMBL
GenPept
RNA Seq Atlas 64983