Version 5.4
| Mus musculus Gene: Nrxn2 | |||||||||||||||
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| Summary | |||||||||||||||
| InnateDB Gene | IDBG-136514.6 | ||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||
| Gene Symbol | Nrxn2 | ||||||||||||||
| Gene Name | neurexin II | ||||||||||||||
| Synonyms | 6430591O13Rik; mKIAA0921 | ||||||||||||||
| Species | Mus musculus | ||||||||||||||
| Ensembl Gene | ENSMUSG00000033768 | ||||||||||||||
| Encoded Proteins |
neurexin II
neurexin II
neurexin II
neurexin II
neurexin II
neurexin II
neurexin II
neurexin II
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| Protein Structure | |||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||
| Entrez Gene | |||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000110076:
This gene encodes a member of the neurexin gene family. The products of these genes function as cell adhesion molecules and receptors in the vertebrate nervous system. These genes utilize two promoters. The majority of transcripts are produced from the upstream promoter and encode alpha-neurexin isoforms while a smaller number of transcripts are produced from the downstream promoter and encode beta-neuresin isoforms. The alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and have been shown to interact with neurexophilins. The beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. Alternative splicing and the use of alternative promoters may generate thousands of transcript variants (PMID: 12036300, PMID: 11944992).[provided by RefSeq, Jun 2010] |
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| Gene Information | |||||||||||||||
| Type | Protein coding | ||||||||||||||
| Genomic Location | Chromosome 19:6418731-6544169 | ||||||||||||||
| Strand | Forward strand | ||||||||||||||
| Band | A | ||||||||||||||
| Transcripts | |||||||||||||||
| Interactions | |||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||
| NETPATH | |||||||||||||||
| REACTOME | |||||||||||||||
| KEGG |
Cell adhesion molecules (CAMs) pathway
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| INOH | |||||||||||||||
| PID NCI | |||||||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||||||
| NETPATH | |||||||||||||||
| REACTOME | |||||||||||||||
| KEGG |
Cell adhesion molecules (CAMs) pathway
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| INOH | |||||||||||||||
| PID NCI | |||||||||||||||
| Cross-References | |||||||||||||||
| SwissProt | |||||||||||||||
| TrEMBL | E9PUN1 | ||||||||||||||
| UniProt Splice Variant | |||||||||||||||
| Entrez Gene | 18190 | ||||||||||||||
| UniGene | Mm.329616 Mm.414022 Mm.415108 Mm.490219 | ||||||||||||||
| RefSeq | NM_001205234 NM_001205235 NM_020253 | ||||||||||||||
| OMIM | |||||||||||||||
| CCDS | CCDS57132 CCDS57133 | ||||||||||||||
| HPRD | |||||||||||||||
| IMGT | |||||||||||||||
| MGI ID | MGI:1096362 | ||||||||||||||
| MGI Symbol | Nrxn2 | ||||||||||||||
| EMBL | AC124394 AC167245 | ||||||||||||||
| GenPept | |||||||||||||||
| RNA Seq Atlas | 18190 | ||||||||||||||