Version 5.4
Mus musculus Gene: Aqp7
Summary
InnateDB Gene IDBG-136953.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Aqp7
Gene Name aquaporin 7
Synonyms AQP7L; AQPap
Species Mus musculus
Ensembl Gene ENSMUSG00000028427
Encoded Proteins
IDBP-136955
aquaporin 7
IDBP-146437
aquaporin 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165269:
Aquaporins/major intrinsic protein (MIP) are a family of water-selective membrane channels. Aquaporin 7 has greater sequence similarity with AQP3 and AQP9 and they may be a subfamily. Aquaporin 7 and AQP3 are at the same chromosomal location suggesting that 9p13 may be a site of an aquaporin cluster. Aquaporin 7 facilitates water, glycerol and urea transport. It may play an important role in sperm function. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:41033074-41048139
Strand Reverse strand
Band A5
Transcripts
ENSMUST00000030136 ENSMUSP00000030136
ENSMUST00000054945 ENSMUSP00000093007
ENSMUST00000144201
ENSMUST00000149517
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0015250 water channel activity
GO:0015254 glycerol channel activity
GO:0015265 urea channel activity
Biological Process
GO:0006810 transport
GO:0006833 water transport
GO:0007283 spermatogenesis
GO:0015793 glycerol transport
GO:0015840 urea transport
GO:0042493 response to drug
GO:0070295 renal water absorption
GO:0071918 urea transmembrane transport
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005911 cell-cell junction
GO:0016020 membrane
GO:0030529 ribonucleoprotein complex
GO:0031526 brush border membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000165269
View Gene Order
ENSBTAG00000020105
Not yet available
Pathways
NETPATH
REACTOME
REACT_198170
Transport of glycerol from adipocytes to the liver by Aquaporins pathway
REACT_226335
Aquaporin-mediated transport pathway
REACT_259079
Passive transport by Aquaporins pathway
REACT_253400
Transmembrane transport of small molecules pathway
KEGG
mmu03320
PPAR signaling pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_23809
Transport of glycerol from adipocytes to the liver by Aquaporins pathway
REACT_23826
Passive transport by Aquaporins pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_23887
Aquaporin-mediated transport pathway
KEGG
hsa03320
PPAR signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.8728
RefSeq NM_007473 XM_006537559 XM_006537560 XM_006537562
OMIM
CCDS CCDS18055
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca