Version 5.4
Mus musculus Gene: Immp2l
Summary
InnateDB Gene IDBG-136987.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Immp2l
Gene Name IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
Synonyms AI853880; IMP2
Species Mus musculus
Ensembl Gene ENSMUSG00000056899
Encoded Proteins
IDBP-136989
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
IDBP-542197
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
IDBP-536641
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000184903:
This gene encodes a protein involved in processing the signal peptide sequences used to direct mitochondrial proteins to the mitochondria. The encoded protein resides in the mitochondria and is one of the necessary proteins for the catalytic activity of the mitochondrial inner membrane peptidase (IMP) complex. Two variants that encode the same protein have been described for this gene. [provided by RefSeq, Sep 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:41024090-41955588
Strand Forward strand
Band B1
Transcripts
ENSMUST00000080160 ENSMUSP00000079055
ENSMUST00000132121 ENSMUSP00000118779
ENSMUST00000153184
ENSMUST00000140790
ENSMUST00000134965 ENSMUSP00000116441
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008233 peptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0001541 ovarian follicle development
GO:0006508 proteolysis
GO:0006627 protein processing involved in protein targeting to mitochondrion
GO:0007283 spermatogenesis
GO:0008104 protein localization
GO:0030728 ovulation
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0042720 mitochondrial inner membrane peptidase complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000184903
View Gene Order
ENSBTAG00000004398
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu03060
Protein export pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa03060
Protein export pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.363813 Mm.383443
RefSeq NM_053122
OMIM
CCDS
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca