Mus musculus Gene: Acat2
Summary
InnateDB Gene IDBG-137689.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Acat2
Gene Name acetyl-Coenzyme A acetyltransferase 2
Synonyms AW742799; Tcp-1x; Tcp1-rs1
Species Mus musculus
Ensembl Gene ENSMUSG00000023832
Encoded Proteins
acetyl-Coenzyme A acetyltransferase 2
acetyl-Coenzyme A acetyltransferase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000120437:
The product of this gene is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:12942890-12960747
Strand Reverse strand
Band A1
Transcripts
ENSMUST00000007005 ENSMUSP00000007005
ENSMUST00000159697 ENSMUSP00000125066
ENSMUST00000159358
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0003985 acetyl-CoA C-acetyltransferase activity
GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups
Biological Process
GO:0008152 metabolic process
GO:0008610 lipid biosynthetic process
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Valine, leucine and isoleucine degradation pathway
Lysine degradation pathway
Synthesis and degradation of ketone bodies pathway
Terpenoid backbone biosynthesis pathway
Tryptophan metabolism pathway
Propanoate metabolism pathway
Pyruvate metabolism pathway
Butanoate metabolism pathway
Glyoxylate and dicarboxylate metabolism pathway
Fatty acid degradation pathway
Fat digestion and absorption pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Terpenoid backbone biosynthesis pathway
Pyruvate metabolism pathway
Valine, leucine and isoleucine degradation pathway
Butanoate metabolism pathway
Propanoate metabolism pathway
Glyoxylate and dicarboxylate metabolism pathway
Tryptophan metabolism pathway
Synthesis and degradation of ketone bodies pathway
Fatty acid degradation pathway
Lysine degradation pathway
Fat digestion and absorption pathway
INOH
Tryptophan degradation pathway
Butanoate metabolism pathway
Citrate cycle pathway
Pyruvate metabolism pathway
Lysine degradation pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.439711
RefSeq NM_009338 XM_006523314
OMIM
CCDS CCDS37437
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas