InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Rspo2

Summary

InnateDB Gene

IDBG-137897.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rspo2

Gene Name

R-spondin 2 homolog (Xenopus laevis)

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000051920

Encoded Proteins

IDBP-137899

R-spondin 2 homolog (Xenopus laevis)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000147655:
R-spondins (RSPOs), such as RSPO2, are secreted proteins that regulate beta-catenin (CTNNB1; MIM 116806) signaling (Kim et al., 2006 [PubMed 16357527]).[supplied by OMIM, Mar 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 15:43020811-43170818

Strand

Reverse strand

Band

B3.2

Transcripts

ENSMUST00000063492

ENSMUSP00000067325

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005102	receptor binding
GO:0008201	heparin binding

Biological Process

GO:0001649	osteoblast differentiation
GO:0016055	Wnt signaling pathway
GO:0030282	bone mineralization
GO:0035115	embryonic forelimb morphogenesis
GO:0035116	embryonic hindlimb morphogenesis
GO:0060437	lung growth
GO:0060441	epithelial tube branching involved in lung morphogenesis
GO:0060535	trachea cartilage morphogenesis
GO:0090263	positive regulation of canonical Wnt signaling pathway