Mus musculus Gene: Eif3e
Summary
InnateDB Gene IDBG-137965.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Eif3e
Gene Name eukaryotic translation initiation factor 3, subunit E
Synonyms 48kDa; eIF3-p46; eIF3-p48; Eif3s6; Int6;
Species Mus musculus
Ensembl Gene ENSMUSG00000022336
Encoded Proteins
eukaryotic translation initiation factor 3, subunit E
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000104408:
Gene Information
Type Protein coding
Genomic Location Chromosome 15:43250040-43282736
Strand Reverse strand
Band B3.2
Transcripts
ENSMUST00000022960 ENSMUSP00000022960
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 89 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 89 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003743 translation initiation factor activity
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
GO:0047485 protein N-terminus binding
Biological Process
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0001731 formation of translation preinitiation complex
GO:0006413 translational initiation
GO:0006446 regulation of translational initiation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005852 eukaryotic translation initiation factor 3 complex
GO:0016020 membrane
GO:0016282 eukaryotic 43S preinitiation complex
GO:0016605 PML body
GO:0033290 eukaryotic 48S preinitiation complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S pathway
Translation pathway
Translation initiation complex formation pathway
Metabolism of proteins pathway
Cap-dependent Translation Initiation pathway
Eukaryotic Translation Initiation pathway
Formation of a pool of free 40S subunits pathway
Gene Expression pathway
L13a-mediated translational silencing of Ceruloplasmin expression pathway
Ribosomal scanning and start codon recognition pathway
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
Formation of the ternary complex, and subsequently, the 43S complex pathway
KEGG
RNA transport pathway
Hepatitis C pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Eukaryotic Translation Initiation pathway
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S pathway
Formation of a pool of free 40S subunits pathway
Translation pathway
Translation initiation complex formation pathway
Metabolism of proteins pathway
Cap-dependent Translation Initiation pathway
Ribosomal scanning and start codon recognition pathway
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
Formation of the ternary complex, and subsequently, the 43S complex pathway
L13a-mediated translational silencing of Ceruloplasmin expression pathway
Gene Expression pathway
Formation of the ternary complex, and subsequently, the 43S complex pathway
L13a-mediated translational silencing of Ceruloplasmin expression pathway
Gene Expression pathway
Eukaryotic Translation Initiation pathway
Cap-dependent Translation Initiation pathway
Formation of a pool of free 40S subunits pathway
Translation pathway
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
Metabolism of proteins pathway
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S pathway
Translation initiation complex formation pathway
Ribosomal scanning and start codon recognition pathway
KEGG
RNA transport pathway
Hepatitis C pathway
INOH
PID BIOCARTA
PID NCI
HIF-2-alpha transcription factor network
Cross-References
SwissProt P60229
TrEMBL Q3UIG0 Q6LCK2 Q9CT23
UniProt Splice Variant
Entrez Gene 16341
UniGene Mm.289992 Mm.426227
RefSeq NM_008388
OMIM
CCDS CCDS27452
HPRD
IMGT
MGI ID MGI:99257
MGI Symbol Eif3e
EMBL AK011436 AK145059 AK146936 AK161650 AK165929 BC029177 CH466541 S75221 S75223 U54563
GenPept AAC00046 AAC00047 AAC53346 AAH29177 BAB27621 BAE26211 BAE27546 BAE36512 BAE38465 EDL08753
RNA Seq Atlas 16341