Homo sapiens Gene: PRDM9
Summary
InnateDB Gene IDBG-13910.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRDM9
Gene Name PR domain containing 9
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000164256
Encoded Proteins
PR domain containing 9
PR domain containing 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The PR domain is a protein-protein interaction module of about 100 amino acids. PR domain-containing proteins, such as PRDM9, are often involved in transcriptional regulation (Jiang and Huang, 2000 [PubMed 10668202]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:23507155-23528597
Strand Forward strand
Band p14.2
Transcripts
ENST00000296682 ENSP00000296682
ENST00000502755 ENSP00000425471
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0010844 recombination hotspot binding
GO:0042800 histone methyltransferase activity (H3-K4 specific)
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006311 meiotic gene conversion
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007283 spermatogenesis
GO:0010845 positive regulation of reciprocal meiotic recombination
GO:0016571 histone methylation
GO:0034968 histone lysine methylation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0051568 histone H3-K4 methylation
GO:0060903 positive regulation of meiosis I
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
Orthologs
Species
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
Low
Tentative data, uncurated. RBBH derived.
Pathways
NETPATH
REACTOME
Cell Cycle pathway
Meiotic recombination pathway
Meiosis pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q9NQV7
TrEMBL D2E453 D2KI85 D6RD68
UniProt Splice Variant
Entrez Gene 56979
UniGene Hs.283096
RefSeq NM_020227
HUGO HGNC:13994
OMIM 609760
CCDS CCDS43307
HPRD 17905
IMGT
EMBL AC025451 AF275816 AK301776 DQ388610 FJ899866 FJ899873 FJ899885 FJ899887 FJ899899 GU216223
GenPept AAF87242 ABD47939 ADA68126 ADA68133 ADA68145 ADA68147 ADA68159 ADA71146 BAG63234
RNA Seq Atlas 56979