Version 5.4
Mus musculus Gene: Ap1m2
Summary
InnateDB Gene IDBG-139938.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ap1m2
Gene Name adaptor protein complex AP-1, mu 2 subunit
Synonyms [m]1B; D9Ertd818e; mu1B
Species Mus musculus
Ensembl Gene ENSMUSG00000003309
Encoded Proteins
IDBP-139940
adaptor protein complex AP-1, mu 2 subunit
IDBP-249654
adaptor protein complex AP-1, mu 2 subunit
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000129354:
This gene encodes a subunit of the heterotetrameric adaptor-related protein comlex 1 (AP-1), which belongs to the adaptor complexes medium subunits family. This protein is capable of interacting with tyrosine-based sorting signals. [provided by RefSeq, Jul 2008]
This gene encodes a subunit of the heterotetrameric adaptor-related protein comlex 1 (AP-1), which belongs to the adaptor complexes medium subunits family. This protein is capable of interacting with tyrosine-based sorting signals. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:21295457-21312333
Strand Reverse strand
Band A3
Transcripts
ENSMUST00000003397 ENSMUSP00000003397
ENSMUST00000115433 ENSMUSP00000111093
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006810 transport
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0005802 trans-Golgi network
GO:0030131 clathrin adaptor complex
GO:0030665 clathrin-coated vesicle membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000129354
View Gene Order
ENSBTAG00000021160
Not yet available
Pathways
NETPATH
REACTOME
REACT_209837
Membrane Trafficking pathway
REACT_231722
Lysosome Vesicle Biogenesis pathway
REACT_230745
Immune System pathway
REACT_232671
Golgi Associated Vesicle Biogenesis pathway
REACT_196550
MHC class II antigen presentation pathway
REACT_243409
trans-Golgi Network Vesicle Budding pathway
REACT_234979
Clathrin derived vesicle budding pathway
REACT_229531
Adaptive Immune System pathway
KEGG
mmu04142
Lysosome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_121399
MHC class II antigen presentation pathway
REACT_11103
Nef mediated downregulation of MHC class I complex cell surface expression pathway
REACT_19287
Lysosome Vesicle Biogenesis pathway
REACT_19400
Golgi Associated Vesicle Biogenesis pathway
REACT_19187
Clathrin derived vesicle budding pathway
REACT_11235
trans-Golgi Network Vesicle Budding pathway
REACT_11149
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_6185
HIV Infection pathway
REACT_6835
The role of Nef in HIV-1 replication and disease pathogenesis pathway
REACT_6288
Host Interactions of HIV factors pathway
REACT_116125
Disease pathway
REACT_11123
Membrane Trafficking pathway
REACT_219531
Golgi Associated Vesicle Biogenesis pathway
REACT_213138
Immune System pathway
REACT_216751
Clathrin derived vesicle budding pathway
REACT_211133
MHC class II antigen presentation pathway
REACT_211153
trans-Golgi Network Vesicle Budding pathway
REACT_214469
Adaptive Immune System pathway
REACT_205891
Lysosome Vesicle Biogenesis pathway
REACT_213260
Membrane Trafficking pathway
KEGG
hsa04142
Lysosome pathway
INOH
PID NCI
Cross-References
SwissProt Q9WVP1
TrEMBL
UniProt Splice Variant
Entrez Gene 11768
UniGene
RefSeq NM_001110300 NM_009678
OMIM
CCDS CCDS22902 CCDS52734
HPRD
IMGT
MGI ID MGI:1336974
MGI Symbol Ap1m2
EMBL AF067146 AF139406 AF139407 AF139408 AF139409 AF139410 AF139411 AF139412 AF139413 AF139414 AF139415 AF139416 AK010478 BC003704
GenPept AAD28085 AAF61815 AAH03704 BAB26971
RNA Seq Atlas 11768

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca