Version 5.4
Mus musculus Gene: Slc25a15
Summary
InnateDB Gene IDBG-140599.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc25a15
Gene Name solute carrier family 25 (mitochondrial carrier ornithine transporter), member 15
Synonyms D630044L02Rik; Ornt1
Species Mus musculus
Ensembl Gene ENSMUSG00000031482
Encoded Proteins
IDBP-140601
solute carrier family 25 (mitochondrial carrier ornithine transporter), member 15
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000102743:
This gene is a member of the mitochondrial carrier family. The encoded protein transports ornithine across the inner mitochondrial membrane from the cytosol to the mitochondrial matrix. The protein is an essential component of the urea cycle, and functions in ammonium detoxification and biosynthesis of the amino acid arginine. Mutations in this gene result in hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome. There is a pseudogene of this locus on the Y chromosome.[provided by RefSeq, May 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:22375554-22398621
Strand Reverse strand
Band A2
Transcripts
ENSMUST00000033871 ENSMUSP00000033871
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006810 transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000102743
View Gene Order
ENSBTAG00000011647
Not yet available
Pathways
NETPATH
REACTOME
REACT_188937
Metabolism pathway
REACT_246679
Urea cycle pathway
REACT_232845
Metabolism of amino acids and derivatives pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_847
Urea cycle pathway
REACT_13
Metabolism of amino acids and derivatives pathway
REACT_111217
Metabolism pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9WVD5
TrEMBL Q543E2 Q6P8P5
UniProt Splice Variant
Entrez Gene 18408
UniGene Mm.200907 Mm.412941
RefSeq NM_181325 XM_006509026
OMIM
CCDS CCDS22175
HPRD
IMGT
MGI ID MGI:1342274
MGI Symbol Slc25a15
EMBL AF133914 AK052758 AK142223 AK145966 BC061143 CH466580
GenPept AAD45252 AAH61143 BAC35136 BAE24984 BAE26791 EDL32895
RNA Seq Atlas 18408

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca