Version 5.4
Mus musculus Gene: Stx5a
Summary
InnateDB Gene IDBG-140633.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Stx5a
Gene Name syntaxin 5A
Synonyms 0610031F24Rik; D19Ertd627e; Stx5
Species Mus musculus
Ensembl Gene ENSMUSG00000010110
Encoded Proteins
IDBP-140635
syntaxin 5A
IDBP-140637
syntaxin 5A
IDBP-704945
IDBP-705224
IDBP-705349
IDBP-705249
IDBP-704838
IDBP-705085
IDBP-704715
IDBP-704408
IDBP-704243
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000162236:
This gene encodes a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for v-SNAREs (vesicle-SNAP receptors), permitting specific synaptic vesicle docking and fusion. The encoded protein regulates endoplasmic reticulum to Golgi transport and plays a critical role in autophagy. Autoantibodies targeting the encoded protein may be a diagnostic marker for endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:8741413-8756069
Strand Forward strand
Band A
Transcripts
ENSMUST00000073430 ENSMUSP00000073136
ENSMUST00000010254 ENSMUSP00000010254
ENSMUST00000176314 ENSMUSP00000135348
ENSMUST00000176570 ENSMUSP00000134892
ENSMUST00000176013 ENSMUSP00000135465
ENSMUST00000176093
ENSMUST00000176968 ENSMUSP00000135468
ENSMUST00000177322 ENSMUSP00000135624
ENSMUST00000175901 ENSMUSP00000134951
ENSMUST00000176260
ENSMUST00000176844
ENSMUST00000176404
ENSMUST00000175834
ENSMUST00000177373 ENSMUSP00000134794
ENSMUST00000175642
ENSMUST00000176009
ENSMUST00000176182
ENSMUST00000176381 ENSMUSP00000134854
ENSMUST00000175872 ENSMUSP00000135416
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 28 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005484 SNAP receptor activity
GO:0005515 protein binding
GO:0047485 protein N-terminus binding
Biological Process
GO:0006886 intracellular protein transport
GO:0006888 ER to Golgi vesicle-mediated transport
GO:0016192 vesicle-mediated transport
GO:0042147 retrograde transport, endosome to Golgi
GO:0048280 vesicle fusion with Golgi apparatus
Cellular Component
GO:0000139 Golgi membrane
GO:0005634 nucleus
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031201 SNARE complex
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000162236
View Gene Order
ENSBTAG00000009490
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04130
SNARE interactions in vesicular transport pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04130
SNARE interactions in vesicular transport pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.153061 Mm.454464 Mm.483890
RefSeq NM_001167799 NM_019829
OMIM
CCDS CCDS29542
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca