InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Myst3

Summary

InnateDB Gene

IDBG-141414.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Myst3

Gene Name

MYST histone acetyltransferase (monocytic leukemia) 3

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000031540

Encoded Proteins

IDBP-141416

MYST histone acetyltransferase (monocytic leukemia) 3

IDBP-259711

MYST histone acetyltransferase (monocytic leukemia) 3

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000083168:

Gene Information

Type

Protein coding

Genomic Location

Chromosome 8:22859535-22943259

Strand

Forward strand

Band

Transcripts

ENSMUST00000044331	ENSMUSP00000038181
ENSMUST00000110696	ENSMUSP00000106324
ENSMUST00000130718

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	3 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	25 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0004402	histone acetyltransferase activity
GO:0005515	protein binding
GO:0008134	transcription factor binding
GO:0008270	zinc ion binding
GO:0016407	acetyltransferase activity
GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups

Biological Process

GO:0003007	heart morphogenesis
GO:0006334	nucleosome assembly
GO:0006355	regulation of transcription, DNA-templated
GO:0006473	protein acetylation
GO:0016573	histone acetylation
GO:0030099	myeloid cell differentiation
GO:0035019	somatic stem cell maintenance
GO:0035162	embryonic hemopoiesis
GO:0035909	aorta morphogenesis
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043966	histone H3 acetylation
GO:0045892	negative regulation of transcription, DNA-templated
GO:0045893	positive regulation of transcription, DNA-templated
GO:0060325	face morphogenesis
GO:0090398	cellular senescence

Cellular Component

GO:0000786	nucleosome
GO:0005634	nucleus
GO:0005794	Golgi apparatus
GO:0016605	PML body
GO:0070776	MOZ/MORF histone acetyltransferase complex

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000083168

View Gene Order

ENSBTAG00000004015

Not yet available

Pathway Predictions based on Human Orthology Data

NETPATH

REACTOME

REACT_172610

HATs acetylate histones pathway

REACT_172623

Chromatin organization pathway

REACT_172633

Chromatin modifying enzymes pathway

KEGG

INOH

PID NCI

Cross-References

SwissProt

TrEMBL

G3X940 Q3UFW4 Q3UPM9 Q3V1G6 Q8C6L0

UniProt Splice Variant

Entrez Gene

244349

UniGene

Mm.182776 Mm.457502

RefSeq

NM_001081149 XM_006509112 XM_006509113

OMIM

CCDS

CCDS40294

HPRD

IMGT

MGI ID

MGI:2442415

MGI Symbol

Kat6a

EMBL

AC115361 AC142414 AK054354 AK132474 AK143408 AK148261 CH466580

GenPept

BAC35748 BAE21185 BAE25366 BAE28445 EDL32873

RNA Seq Atlas

244349