Mus musculus Gene: Rps5
Summary
InnateDB Gene IDBG-143745.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rps5
Gene Name ribosomal protein S5
Synonyms AA617411
Species Mus musculus
Ensembl Gene ENSMUSG00000012848
Encoded Proteins
ribosomal protein S5
ribosomal protein S5
ribosomal protein S5
ribosomal protein S5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000083845:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S7P family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:12922290-12926686
Strand Forward strand
Band A1
Transcripts
ENSMUST00000004554 ENSMUSP00000004554
ENSMUST00000108539 ENSMUSP00000104179
ENSMUST00000147435 ENSMUSP00000118798
ENSMUST00000139349
ENSMUST00000131795
ENSMUST00000137329 ENSMUSP00000121961
ENSMUST00000127669
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 80 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 80 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006412 translation
GO:0006450 regulation of translational fidelity
Cellular Component
GO:0015935 small ribosomal subunit
GO:0016020 membrane
GO:0022627 cytosolic small ribosomal subunit
GO:0030529 ribonucleoprotein complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Ribosome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
L13a-mediated translational silencing of Ceruloplasmin expression pathway
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) pathway
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
Translation initiation complex formation pathway
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S pathway
Formation of a pool of free 40S subunits pathway
Formation of the ternary complex, and subsequently, the 43S complex pathway
Ribosomal scanning and start codon recognition pathway
Eukaryotic Translation Termination pathway
Peptide chain elongation pathway
Eukaryotic Translation Elongation pathway
SRP-dependent cotranslational protein targeting to membrane pathway
Viral mRNA Translation pathway
Eukaryotic Translation Initiation pathway
Influenza Infection pathway
Nonsense-Mediated Decay (NMD) pathway
Influenza Viral RNA Transcription and Replication pathway
Translation pathway
Metabolism of proteins pathway
Cap-dependent Translation Initiation pathway
Influenza Life Cycle pathway
Gene Expression pathway
Disease pathway
SRP-dependent cotranslational protein targeting to membrane pathway
Formation of the ternary complex, and subsequently, the 43S complex pathway
L13a-mediated translational silencing of Ceruloplasmin expression pathway
Peptide chain elongation pathway
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
Gene Expression pathway
Eukaryotic Translation Initiation pathway
Cap-dependent Translation Initiation pathway
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) pathway
Formation of a pool of free 40S subunits pathway
Translation pathway
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
Metabolism of proteins pathway
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S pathway
Translation initiation complex formation pathway
Nonsense-Mediated Decay (NMD) pathway
Ribosomal scanning and start codon recognition pathway
Eukaryotic Translation Termination pathway
Eukaryotic Translation Elongation pathway
KEGG
Ribosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_009095 XM_006539682
OMIM
CCDS CCDS20817
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas