Version 5.4
| Mus musculus Gene: Sqle | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-143960.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Sqle | ||||||||
| Gene Name | squalene epoxidase | ||||||||
| Synonyms | AI323792 | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000022351 | ||||||||
| Encoded Proteins |
squalene epoxidase
squalene epoxidase
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000104549:
Squalene epoxidase catalyzes the first oxygenation step in sterol biosynthesis and is thought to be one of the rate-limiting enzymes in this pathway. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 15:59315077-59331192 | ||||||||
| Strand | Forward strand | ||||||||
| Band | D1 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
Activation of gene expression by SREBF (SREBP) pathway
Regulation of cholesterol biosynthesis by SREBP (SREBF) pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Cholesterol biosynthesis pathway
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| KEGG |
Steroid biosynthesis pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Activation of gene expression by SREBF (SREBP) pathway
Regulation of cholesterol biosynthesis by SREBP (SREBF) pathway
Cholesterol biosynthesis pathway
Metabolism of lipids and lipoproteins pathway
Metabolism pathway
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| KEGG |
Steroid biosynthesis pathway
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| INOH |
Steroids metabolism pathway
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| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | P52019 | ||||||||
| TrEMBL | Q3TQK8 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 20775 | ||||||||
| UniGene | Mm.296169 | ||||||||
| RefSeq | NM_009270 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS27497 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:109296 | ||||||||
| MGI Symbol | Sqle | ||||||||
| EMBL | AK163502 BC042781 BC056361 CH466545 D42048 | ||||||||
| GenPept | AAH42781 AAH56361 BAA07649 BAE37374 EDL29326 | ||||||||
| RNA Seq Atlas | 20775 | ||||||||