Version 5.4
Mus musculus Gene: Mnx1
Summary
InnateDB Gene IDBG-144591.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mnx1
Gene Name motor neuron and pancreas homeobox 1
Synonyms HB9; Hlxb9; MNR2
Species Mus musculus
Ensembl Gene ENSMUSG00000001566
Encoded Proteins
IDBP-144593
motor neuron and pancreas homeobox 1
IDBP-625205
motor neuron and pancreas homeobox 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000130675:
This gene encodes a nuclear protein, which contains a homeobox domain and is a transcription factor. Mutations in this gene result in Currarino syndrome, an autosomic dominant congenital malformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:29473034-29478470
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000001608 ENSMUSP00000001608
ENSMUST00000165512 ENSMUSP00000129503
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0001764 neuron migration
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0008045 motor neuron axon guidance
GO:0009791 post-embryonic development
GO:0021520 spinal cord motor neuron cell fate specification
GO:0021675 nerve development
GO:0021904 dorsal/ventral neural tube patterning
GO:0021953 central nervous system neuron differentiation
GO:0030182 neuron differentiation
GO:0031016 pancreas development
GO:0031018 endocrine pancreas development
GO:0048667 cell morphogenesis involved in neuron differentiation
GO:0048812 neuron projection morphogenesis
GO:0060539 diaphragm development
GO:0060541 respiratory system development
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000130675
View Gene Order
ENSBTAG00000030876
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04950
Maturity onset diabetes of the young pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04950
Maturity onset diabetes of the young pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.103760 Mm.484672
RefSeq NM_019944
OMIM
CCDS CCDS19150
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca