Version 5.4
Mus musculus Gene: Slc1a5
Summary
InnateDB Gene IDBG-146844.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc1a5
Gene Name solute carrier family 1 (neutral amino acid transporter), member 5
Synonyms AAAT; ASCT2; ATBO; M7V1; M7VS1; R16; RDRC; Slc1a7
Species Mus musculus
Ensembl Gene ENSMUSG00000001918
Encoded Proteins
IDBP-264415
solute carrier family 1 (neutral amino acid transporter), member 5
IDBP-537389
solute carrier family 1 (neutral amino acid transporter), member 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000105281:
The SLC1A5 gene encodes a sodium-dependent neutral amino acid transporter that can act as a receptor for RD114/type D retrovirus (Larriba et al., 2001 [PubMed 11781704]).[supplied by OMIM, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:16781346-16798274
Strand Forward strand
Band A2
Transcripts
ENSMUST00000108496 ENSMUSP00000104136
ENSMUST00000127401
ENSMUST00000135817 ENSMUSP00000116654
ENSMUST00000131664
ENSMUST00000147814
ENSMUST00000134407
ENSMUST00000141349
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0015171 amino acid transmembrane transporter activity
GO:0015175 neutral amino acid transmembrane transporter activity
GO:0015194 L-serine transmembrane transporter activity
GO:0017153 sodium:dicarboxylate symporter activity
Biological Process
GO:0003333 amino acid transmembrane transport
GO:0006835 dicarboxylic acid transport
GO:0006860 extracellular amino acid transport
GO:0015804 neutral amino acid transport
GO:0015825 L-serine transport
Cellular Component
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000105281
View Gene Order
ENSBTAG00000013577
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04974
Protein digestion and absorption pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_13796
Amino acid transport across the plasma membrane pathway
REACT_19397
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
hsa04974
Protein digestion and absorption pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.1056
RefSeq NM_009201
OMIM
CCDS CCDS39785
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca