InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Tnks

Summary

InnateDB Gene

IDBG-148532.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tnks

Gene Name

tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase

Synonyms

4930554K12Rik; AI662855; ARTD5; C86528; D130072O21Rik; mTNKS1; TANK1

Species

Mus musculus

Ensembl Gene

ENSMUSG00000031529

Encoded Proteins

IDBP-148534

tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000173273:

Gene Information

Type

Protein coding

Genomic Location

Chromosome 8:34829179-34965690

Strand

Reverse strand

Band

Transcripts

ENSMUST00000033929

ENSMUSP00000033929

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	22 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003950	NAD+ ADP-ribosyltransferase activity
GO:0005515	protein binding
GO:0008270	zinc ion binding

Biological Process

GO:0000209	protein polyubiquitination
GO:0006471	protein ADP-ribosylation
GO:0007067	mitotic nuclear division
GO:0015031	protein transport
GO:0016055	Wnt signaling pathway
GO:0018105	peptidyl-serine phosphorylation
GO:0018107	peptidyl-threonine phosphorylation
GO:0032212	positive regulation of telomere maintenance via telomerase
GO:0043392	negative regulation of DNA binding
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0051028	mRNA transport
GO:0051225	spindle assembly
GO:0070198	protein localization to chromosome, telomeric region
GO:0070212	protein poly-ADP-ribosylation
GO:0070213	protein auto-ADP-ribosylation
GO:0090263	positive regulation of canonical Wnt signaling pathway

Cellular Component

GO:0000139	Golgi membrane
GO:0000775	chromosome, centromeric region
GO:0000781	chromosome, telomeric region
GO:0000784	nuclear chromosome, telomeric region
GO:0000922	spindle pole
GO:0005634	nucleus
GO:0005643	nuclear pore
GO:0005794	Golgi apparatus
GO:0005829	cytosol
GO:0031965	nuclear membrane