Version 5.4
Mus musculus Gene: Ldoc1
Summary
InnateDB Gene IDBG-148878.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ldoc1
Gene Name leucine zipper, down-regulated in cancer 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000057615
Encoded Proteins
IDBP-148880
leucine zipper, down-regulated in cancer 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000182195:
The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:61709497-61710955
Strand Forward strand
Band A6
Transcripts
ENSMUST00000075983 ENSMUSP00000075366
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 35 interaction(s) predicted by orthology.
Predicted by orthology
Total 35 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000182195
View Gene Order
Cross-References
SwissProt Q7TPY9
TrEMBL
UniProt Splice Variant
Entrez Gene 434784
UniGene Mm.23468
RefSeq NM_001018087
OMIM
CCDS CCDS30163
HPRD
IMGT
MGI ID MGI:2685212
MGI Symbol Ldoc1
EMBL AK137057 AL672025 BC052689
GenPept AAH52689 BAE23221 CAM20842
RNA Seq Atlas 434784

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca