Mus musculus Gene: Adcyap1r1
Summary
InnateDB Gene IDBG-150150.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Adcyap1r1
Gene Name adenylate cyclase activating polypeptide 1 receptor 1
Synonyms 2900024I10Rik; AI846590; PAC1; PAC1R; PACAP1-R;
Species Mus musculus
Ensembl Gene ENSMUSG00000029778
Encoded Proteins
adenylate cyclase activating polypeptide 1 receptor 1
adenylate cyclase activating polypeptide 1 receptor 1
adenylate cyclase activating polypeptide 1 receptor 1
adenylate cyclase activating polypeptide 1 receptor 1
adenylate cyclase activating polypeptide 1 receptor 1
adenylate cyclase activating polypeptide 1 receptor 1
adenylate cyclase activating polypeptide 1 receptor 1
adenylate cyclase activating polypeptide 1 receptor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000078549:
This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:55451978-55501451
Strand Forward strand
Band B3
Transcripts
ENSMUST00000070736 ENSMUSP00000063784
ENSMUST00000070756 ENSMUSP00000066902
ENSMUST00000166962 ENSMUSP00000130742
ENSMUST00000167484 ENSMUSP00000131641
ENSMUST00000172084 ENSMUSP00000127319
ENSMUST00000165857 ENSMUSP00000129614
ENSMUST00000167234 ENSMUSP00000126994
ENSMUST00000165786 ENSMUSP00000130923
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G-protein coupled receptor activity
GO:0004999 vasoactive intestinal polypeptide receptor activity
GO:0005515 protein binding
GO:0008179 adenylate cyclase binding
GO:0030306 ADP-ribosylation factor binding
GO:0042923 neuropeptide binding
Biological Process
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007202 activation of phospholipase C activity
GO:0007283 spermatogenesis
GO:0010524 positive regulation of calcium ion transport into cytosol
GO:0019933 cAMP-mediated signaling
GO:0030154 cell differentiation
GO:0030819 positive regulation of cAMP biosynthetic process
GO:0032355 response to estradiol
GO:0033555 multicellular organismal response to stress
GO:0042493 response to drug
GO:0045471 response to ethanol
GO:0046545 development of primary female sexual characteristics
GO:0060548 negative regulation of cell death
GO:0060732 positive regulation of inositol phosphate biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005791 rough endoplasmic reticulum
GO:0005886 plasma membrane
GO:0005901 caveola
GO:0005923 tight junction
GO:0009986 cell surface
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0043005 neuron projection
GO:0043235 receptor complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
G alpha (s) signalling events pathway
Glucagon-type ligand receptors pathway
GPCR downstream signaling pathway
Signaling by GPCR pathway
Class B/2 (Secretin family receptors) pathway
GPCR ligand binding pathway
Signalling by NGF pathway
NGF signalling via TRKA from the plasma membrane pathway
Signal Transduction pathway
NGF-independant TRKA activation pathway
Activation of TRKA receptors pathway
KEGG
Neuroactive ligand-receptor interaction pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
G alpha (s) signalling events pathway
Signalling by NGF pathway
NGF-independant TRKA activation pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
Glucagon-type ligand receptors pathway
NGF signalling via TRKA from the plasma membrane pathway
GPCR ligand binding pathway
Activation of TRKA receptors pathway
Class B/2 (Secretin family receptors) pathway
NGF-independant TRKA activation pathway
Glucagon-type ligand receptors pathway
Signaling by GPCR pathway
Activation of TRKA receptors pathway
G alpha (s) signalling events pathway
Signal Transduction pathway
NGF signalling via TRKA from the plasma membrane pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
Signalling by NGF pathway
Class B/2 (Secretin family receptors) pathway
KEGG
Neuroactive ligand-receptor interaction pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL E9Q968
UniProt Splice Variant
Entrez Gene 11517
UniGene Mm.397683 Mm.403675
RefSeq NM_007407 NM_001025372 XM_006505391
OMIM
CCDS CCDS20167 CCDS20166
HPRD
IMGT
MGI ID MGI:108449
MGI Symbol Adcyap1r1
EMBL AC069309
GenPept
RNA Seq Atlas 11517