Homo sapiens Gene: SRGAP3
Summary
InnateDB Gene IDBG-15048.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SRGAP3
Gene Name SLIT-ROBO Rho GTPase activating protein 3
Synonyms ARHGAP14; MEGAP; SRGAP2; WRP;
Species Homo sapiens
Ensembl Gene ENSG00000196220
Encoded Proteins
SLIT-ROBO Rho GTPase activating protein 3
SLIT-ROBO Rho GTPase activating protein 3
SLIT-ROBO Rho GTPase activating protein 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:8980591-9363053
Strand Reverse strand
Band p25.3
Transcripts
ENST00000383836 ENSP00000373347
ENST00000360413 ENSP00000353587
ENST00000433332
ENST00000491467
ENST00000520860
ENST00000518265
ENST00000475560
ENST00000485983
ENST00000480750
ENST00000470951
ENST00000490348
ENST00000490889
ENST00000618999 ENSP00000482666
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0043547 positive regulation of GTPase activity
GO:0051056 regulation of small GTPase mediated signal transduction
Cellular Component
GO:0005622 intracellular
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Developmental Biology pathway
Signaling by Rho GTPases pathway
Axon guidance pathway
Signal Transduction pathway
Rho GTPase cycle pathway
Signaling by Robo receptor pathway
Inactivation of Cdc42 and Rac pathway
KEGG
Axon guidance pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.610316 Hs.654743
RefSeq NM_001033117 NM_014850 XM_006713433
HUGO
OMIM
CCDS CCDS2572 CCDS33689
HPRD 12108
IMGT
EMBL
GenPept
RNA Seq Atlas