Homo sapiens Gene: REXO1
Summary
InnateDB Gene IDBG-15055.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol REXO1
Gene Name REX1, RNA exonuclease 1 homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000079313
Encoded Proteins
REX1, RNA exonuclease 1 homolog (S. cerevisiae)
REX1, RNA exonuclease 1 homolog (S. cerevisiae)
REX1, RNA exonuclease 1 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:1815246-1848463
Strand Reverse strand
Band p13.3
Transcripts
ENST00000170168 ENSP00000170168
ENST00000590936 ENSP00000468713
ENST00000586343 ENSP00000481515
ENST00000587524
ENST00000587404
ENST00000588743 ENSP00000480368
ENST00000586291
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0004527 exonuclease activity
Biological Process
GO:0090305 nucleic acid phosphodiester bond hydrolysis
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.192477 Hs.601776
RefSeq NM_020695
HUGO
OMIM
CCDS CCDS32866
HPRD 15478
IMGT
EMBL
GenPept
RNA Seq Atlas