Version 5.4
| Mus musculus Gene: Sis | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-151868.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Sis | ||||||||
| Gene Name | sucrase isomaltase (alpha-glucosidase) | ||||||||
| Synonyms | 2010204N08Rik; SI; Si-s | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000027790 | ||||||||
| Encoded Proteins |
sucrase isomaltase (alpha-glucosidase)
sucrase isomaltase (alpha-glucosidase)
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000090402:
This gene encodes a sucrase-isomaltase enzyme that is expressed in the intestinal brush border. The encoded protein is synthesized as a precursor protein that is cleaved by pancreatic proteases into two enzymatic subunits sucrase and isomaltase. These two subunits heterodimerize to form the sucrose-isomaltase complex. This complex is essential for the digestion of dietary carbohydrates including starch, sucrose and isomaltose. Mutations in this gene are the cause of congenital sucrase-isomaltase deficiency.[provided by RefSeq, Apr 2010] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 3:72888557-72967863 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | E3 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME | |||||||||
| KEGG |
Starch and sucrose metabolism pathway
Galactose metabolism pathway
Carbohydrate digestion and absorption pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Digestion of dietary carbohydrate pathway
Myoclonic epilepsy of Lafora pathway
Metabolism of carbohydrates pathway
Metabolism pathway
Disease pathway
Glycogen storage diseases pathway
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| KEGG |
Galactose metabolism pathway
Starch and sucrose metabolism pathway
Carbohydrate digestion and absorption pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | F8VQM5 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 69983 | ||||||||
| UniGene | Mm.261054 | ||||||||
| RefSeq | XM_006502044 NM_001081137 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS38454 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:1917233 | ||||||||
| MGI Symbol | Sis | ||||||||
| EMBL | AC102399 AC164406 | ||||||||
| GenPept | |||||||||
| RNA Seq Atlas | 69983 | ||||||||