Version 5.4
Mus musculus Gene: Pkib
Summary
InnateDB Gene IDBG-152506.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pkib
Gene Name protein kinase inhibitor beta, cAMP dependent, testis specific
Synonyms Pkibeta; Prkacn2
Species Mus musculus
Ensembl Gene ENSMUSG00000019876
Encoded Proteins
IDBP-152508
protein kinase inhibitor beta, cAMP dependent, testis specific
IDBP-152510
protein kinase inhibitor beta, cAMP dependent, testis specific
IDBP-152512
protein kinase inhibitor beta, cAMP dependent, testis specific
IDBP-711252
IDBP-714375
IDBP-711381
IDBP-712705
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135549:
This gene encodes a member of the cAMP-dependent protein kinase inhibitor family. The encoded protein may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and overexpression of this gene may play a role in prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:57631981-57741112
Strand Forward strand
Band B4
Transcripts
ENSMUST00000075992 ENSMUSP00000075374
ENSMUST00000095668 ENSMUSP00000093329
ENSMUST00000066028 ENSMUSP00000067532
ENSMUST00000177473 ENSMUSP00000135835
ENSMUST00000176225
ENSMUST00000176741
ENSMUST00000176354
ENSMUST00000177299
ENSMUST00000175852 ENSMUSP00000135666
ENSMUST00000177438 ENSMUSP00000135774
ENSMUST00000177325 ENSMUSP00000135280
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004862 cAMP-dependent protein kinase inhibitor activity
GO:0016301 kinase activity
Biological Process
GO:0006469 negative regulation of protein kinase activity
GO:0016310 phosphorylation
GO:2000480 negative regulation of cAMP-dependent protein kinase activity
Cellular Component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000135549
View Gene Order
ENSBTAG00000004394
Not yet available
Cross-References
SwissProt
TrEMBL Q3TZU5 Q6P8N5
UniProt Splice Variant
Entrez Gene 18768
UniGene Mm.262135 Mm.416336 Mm.470577
RefSeq NM_001039050 XM_006512605 NM_001039051 NM_001039052 NM_001039053 NM_001190402 NM_008863 XM_006512602 XM_006512603
OMIM
CCDS CCDS23855 CCDS23854
HPRD
IMGT
MGI ID MGI:101937
MGI Symbol Pkib
EMBL AC102647 AC168055 AK156950 AK157521 BC061162 CH466540
GenPept AAH61162 BAE33910 BAE34112 EDL05121 EDL05122
RNA Seq Atlas 18768

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca