Homo sapiens Gene: H2AFV
Summary
InnateDB Gene IDBG-15289.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol H2AFV
Gene Name H2A histone family, member V
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000105968
Encoded Proteins
H2A histone family, member V
H2A histone family, member V
H2A histone family, member V
H2A histone family, member V
H2A histone family, member V
H2A histone family, member V
H2A histone family, member V
H2A histone family, member V
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. Several transcript variants encoding different isoforms, have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:44826791-44848083
Strand Reverse strand
Band p13
Transcripts
ENST00000222690 ENSP00000222690
ENST00000381124 ENSP00000370516
ENST00000308153 ENSP00000308405
ENST00000350771 ENSP00000340708
ENST00000349299 ENSP00000342714
ENST00000437072 ENSP00000397115
ENST00000446531 ENSP00000406901
ENST00000521529 ENSP00000430492
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.
Experimentally validated
Total 29 [view]
Protein-Protein 28 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003677 DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006334 nucleosome assembly
GO:0008150 biological_process
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
Systemic lupus erythematosus pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.597698 Hs.628079
RefSeq NM_012412 NM_138635 NM_201436 NM_201516 NM_201517
HUGO
OMIM
CCDS CCDS47581 CCDS5495 CCDS5496 CCDS5497 CCDS5498
HPRD 13623
IMGT
EMBL
GenPept
RNA Seq Atlas