Version 5.4
Mus musculus Gene: Wdpcp
Summary
InnateDB Gene IDBG-153536.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Wdpcp
Gene Name WD repeat containing planar cell polarity effector
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000020319
Encoded Proteins
IDBP-153538
WD repeat containing planar cell polarity effector
IDBP-532335
WD repeat containing planar cell polarity effector
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143951:
This gene encodes a cytoplasmic WD40 repeat protein. A similar gene in frogs encodes a planar cell polarity protein that plays a critical role in collective cell movement and ciliogenesis by mediating septin localization. Mutations in this gene are associated with Bardet-Biedl syndrome 15 and may also play a role in Meckel-Gruber syndrome. [provided by RefSeq, Feb 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:21572235-21898989
Strand Forward strand
Band A3.1
Transcripts
ENSMUST00000020568 ENSMUSP00000020568
ENSMUST00000131135 ENSMUSP00000120122
ENSMUST00000149757
ENSMUST00000143608
ENSMUST00000156624
ENSMUST00000128794
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001822 kidney development
GO:0002093 auditory receptor cell morphogenesis
GO:0007224 smoothened signaling pathway
GO:0007399 nervous system development
GO:0010762 regulation of fibroblast migration
GO:0016476 regulation of embryonic cell shape
GO:0032185 septin cytoskeleton organization
GO:0032880 regulation of protein localization
GO:0042384 cilium assembly
GO:0042733 embryonic digit morphogenesis
GO:0043010 camera-type eye development
GO:0044782 cilium organization
GO:0045184 establishment of protein localization
GO:0048568 embryonic organ development
GO:0051893 regulation of focal adhesion assembly
GO:0055123 digestive system development
GO:0060021 palate development
GO:0060271 cilium morphogenesis
GO:0060541 respiratory system development
GO:0072358 cardiovascular system development
GO:0090521 glomerular visceral epithelial cell migration
GO:1900027 regulation of ruffle assembly
GO:2000114 regulation of establishment of cell polarity
Cellular Component
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0005930 axoneme
GO:0005938 cell cortex
GO:0016324 apical plasma membrane
GO:0097541 axonemal basal plate
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000143951
View Gene Order
ENSBTAG00000005151
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.138090
RefSeq NM_145425 XM_006514638
OMIM
CCDS CCDS24467
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca