Mus musculus Gene: Gng12
Summary
InnateDB Gene IDBG-153698.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gng12
Gene Name guanine nucleotide binding protein (G protein), gamma 12
Synonyms 2010305F15Rik; AA536815; AI115529; AI314170; AI842738
Species Mus musculus
Ensembl Gene ENSMUSG00000036402
Encoded Proteins
guanine nucleotide binding protein (G protein), gamma 12
guanine nucleotide binding protein (G protein), gamma 12
guanine nucleotide binding protein (G protein), gamma 12
guanine nucleotide binding protein (G protein), gamma 12
guanine nucleotide binding protein (G protein), gamma 12
guanine nucleotide binding protein (G protein), gamma 12
guanine nucleotide binding protein (G protein), gamma 12
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000172380:
Gene Information
Type Protein coding
Genomic Location Chromosome 6:66896397-67021350
Strand Forward strand
Band C1
Transcripts
ENSMUST00000043148 ENSMUSP00000046557
ENSMUST00000114228 ENSMUSP00000109866
ENSMUST00000114227 ENSMUSP00000109865
ENSMUST00000114226 ENSMUSP00000109864
ENSMUST00000114225 ENSMUSP00000109863
ENSMUST00000114224 ENSMUSP00000109862
ENSMUST00000114222 ENSMUSP00000109860
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
GO:0030165 PDZ domain binding
GO:0042301 phosphate ion binding
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0021987 cerebral cortex development
GO:0032496 response to lipopolysaccharide
Cellular Component
GO:0005834 heterotrimeric G-protein complex
GO:0005884 actin filament
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Inwardly rectifying K+ channels pathway
Glucagon-type ligand receptors pathway
Signaling by GPCR pathway
Glucagon signaling in metabolic regulation pathway
Class B/2 (Secretin family receptors) pathway
Integration of energy metabolism pathway
G protein gated Potassium channels pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Metabolism pathway
Activation of GABAB receptors pathway
Aquaporin-mediated transport pathway
Regulation of insulin secretion pathway
Vasopressin regulates renal water homeostasis via Aquaporins pathway
Potassium Channels pathway
GABA B receptor activation pathway
GPCR ligand binding pathway
Transmembrane transport of small molecules pathway
GABA receptor activation pathway
Neuronal System pathway
Signal Transduction pathway
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits pathway
Transmission across Chemical Synapses pathway
Activation of G protein gated Potassium channels pathway
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion pathway
Adrenaline,noradrenaline inhibits insulin secretion pathway
KEGG
Regulation of actin cytoskeleton pathway
MAPK signaling pathway pathway
Chemokine signaling pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Prostacyclin signalling through prostacyclin receptor pathway
Platelet homeostasis pathway
ADP signalling through P2Y purinoceptor 12 pathway
ADP signalling through P2Y purinoceptor 1 pathway
Thromboxane signalling through TP receptor pathway
Thrombin signalling through proteinase activated receptors (PARs) pathway
Vasopressin regulates renal water homeostasis via Aquaporins pathway
G alpha (q) signalling events pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
G alpha (i) signalling events pathway
G beta:gamma signalling through PI3Kgamma pathway
G beta:gamma signalling through PLC beta pathway
G alpha (12/13) signalling events pathway
G alpha (s) signalling events pathway
G alpha (z) signalling events pathway
Glucagon-type ligand receptors pathway
Class B/2 (Secretin family receptors) pathway
G-protein activation pathway
Opioid Signalling pathway
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits pathway
GABA B receptor activation pathway
Presynaptic function of Kainate receptors pathway
Activation of G protein gated Potassium channels pathway
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion pathway
Adrenaline,noradrenaline inhibits insulin secretion pathway
Regulation of insulin secretion pathway
Glucagon signaling in metabolic regulation pathway
Integration of energy metabolism pathway
Transmembrane transport of small molecules pathway
Ca2+ pathway pathway
beta-catenin independent WNT signaling pathway
Signaling by Wnt pathway
Neuronal System pathway
Signaling by GPCR pathway
GABA receptor activation pathway
G protein gated Potassium channels pathway
Platelet activation, signaling and aggregation pathway
G-protein beta:gamma signalling pathway
Activation of GABAB receptors pathway
Signal Transduction pathway
GPCR downstream signaling pathway
Inwardly rectifying K+ channels pathway
Activation of Kainate Receptors upon glutamate binding pathway
Potassium Channels pathway
Transmission across Chemical Synapses pathway
GPCR ligand binding pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Metabolism pathway
Signal amplification pathway
Aquaporin-mediated transport pathway
Hemostasis pathway
Aquaporin-mediated transport pathway
Vasopressin regulates renal water homeostasis via Aquaporins pathway
GABA B receptor activation pathway
Regulation of insulin secretion pathway
Glucagon-type ligand receptors pathway
Signaling by GPCR pathway
G protein gated Potassium channels pathway
GABA receptor activation pathway
Activation of GABAB receptors pathway
Inwardly rectifying K+ channels pathway
Integration of energy metabolism pathway
Transmission across Chemical Synapses pathway
Transmembrane transport of small molecules pathway
Activation of G protein gated Potassium channels pathway
Adrenaline,noradrenaline inhibits insulin secretion pathway
Signal Transduction pathway
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
GPCR ligand binding pathway
Neuronal System pathway
Metabolism pathway
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion pathway
Glucagon signaling in metabolic regulation pathway
Class B/2 (Secretin family receptors) pathway
Potassium Channels pathway
KEGG
Regulation of actin cytoskeleton pathway
MAPK signaling pathway pathway
Chemokine signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt Q9DAS9
TrEMBL
UniProt Splice Variant
Entrez Gene 14701
UniGene Mm.234342 Mm.472558
RefSeq NM_001177556 NM_001177557 NM_001177558 NM_001177559 NM_001177560 NM_025278 XM_006505542
OMIM
CCDS CCDS39502
HPRD
IMGT
MGI ID MGI:1336171
MGI Symbol Gng12
EMBL AK005561 AK033422 AK148765 AK159872 AK162342 AK166035 AK166299 BC040685
GenPept AAH40685 BAB24121 BAC28280 BAE28660 BAE35445 BAE36863 BAE38536 BAE38688
RNA Seq Atlas 14701