Mus musculus Gene: Ctso
Summary
InnateDB Gene IDBG-153915.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ctso
Gene Name cathepsin O
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000028015
Encoded Proteins
cathepsin O
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000256043:
The protein encoded by the gene is a cysteine proteinase and a member of the papain superfamily. This proteolytic enzyme is involved in cellular protein degradation and turnover. The recombinant form of this enzyme was shown to degrade synthetic peptides typically used as substrates for cysteine proteinases and its proteolytic activity was abolished by an inhibitor of cyteine proteinase. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:81932601-81956725
Strand Forward strand
Band E3
Transcripts
ENSMUST00000029649 ENSMUSP00000029649
ENSMUST00000143307
ENSMUST00000155144
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005575 cellular_component
GO:0005764 lysosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Lysosome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
MHC class II antigen presentation pathway
Adaptive Immune System pathway
Immune System pathway
KEGG
Lysosome pathway
INOH
PID NCI
Cross-References
SwissProt Q8BM88
TrEMBL
UniProt Splice Variant
Entrez Gene 229445
UniGene Mm.254642 Mm.420890 Mm.474812
RefSeq NM_177662
OMIM
CCDS CCDS17426
HPRD
IMGT
MGI ID MGI:2139628
MGI Symbol Ctso
EMBL AK034490 AK049470 AK165930 AK166103 BC044664
GenPept AAH44664 BAC28728 BAC33765 BAE38466 BAE38573
RNA Seq Atlas 229445