Version 5.4
Mus musculus Gene: Pigq
Summary
InnateDB Gene IDBG-154069.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pigq
Gene Name phosphatidylinositol glycan anchor biosynthesis, class Q
Synonyms Gpi1; Gpi1h; Gpi1p; Gpih
Species Mus musculus
Ensembl Gene ENSMUSG00000025728
Encoded Proteins
IDBP-154071
phosphatidylinositol glycan anchor biosynthesis, class Q
IDBP-154073
phosphatidylinositol glycan anchor biosynthesis, class Q
IDBP-540187
phosphatidylinositol glycan anchor biosynthesis, class Q
IDBP-539463
phosphatidylinositol glycan anchor biosynthesis, class Q
IDBP-532592
phosphatidylinositol glycan anchor biosynthesis, class Q
IDBP-531677
phosphatidylinositol glycan anchor biosynthesis, class Q
IDBP-531608
phosphatidylinositol glycan anchor biosynthesis, class Q
IDBP-540545
phosphatidylinositol glycan anchor biosynthesis, class Q
IDBP-532075
phosphatidylinositol glycan anchor biosynthesis, class Q
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000007541:
This gene is involved in the first step in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes a N-acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:25926427-25944510
Strand Reverse strand
Band A3.3
Transcripts
ENSMUST00000097368 ENSMUSP00000094981
ENSMUST00000026823 ENSMUSP00000026823
ENSMUST00000133650 ENSMUSP00000117102
ENSMUST00000148045
ENSMUST00000123929 ENSMUSP00000120852
ENSMUST00000139078
ENSMUST00000135253 ENSMUSP00000122239
ENSMUST00000156924
ENSMUST00000140304
ENSMUST00000139226 ENSMUSP00000115447
ENSMUST00000124032
ENSMUST00000145745 ENSMUSP00000119772
ENSMUST00000148307 ENSMUSP00000118632
ENSMUST00000148382 ENSMUSP00000119871
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity
Biological Process
GO:0006506 GPI anchor biosynthetic process
Cellular Component
GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000007541
View Gene Order
ENSBTAG00000016594
Not yet available
Pathways
NETPATH
REACTOME
REACT_244576
Post-translational modification: synthesis of GPI-anchored proteins pathway
REACT_247926
Metabolism of proteins pathway
REACT_236283
Post-translational protein modification pathway
REACT_243945
Synthesis of glycosylphosphatidylinositol (GPI) pathway
KEGG
mmu00563
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00563
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.362054 Mm.407751
RefSeq NM_001291025 NM_011822 XM_006523663 XM_006523664 XM_006523665
OMIM
CCDS CCDS28538 CCDS70774
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca