Version 5.4
Mus musculus Gene: Spock2
Summary
InnateDB Gene IDBG-154392.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Spock2
Gene Name sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
Synonyms AA407235; Gcap26; mKIAA0275
Species Mus musculus
Ensembl Gene ENSMUSG00000058297
Encoded Proteins
IDBP-401298
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
IDBP-624047
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000107742:
This gene encodes a protein which binds with glycosaminoglycans to form part of the extracellular matrix. The protein contains thyroglobulin type-1, follistatin-like, and calcium-binding domains, and has glycosaminoglycan attachment sites in the acidic C-terminal region. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:60106219-60135198
Strand Forward strand
Band B4
Transcripts
ENSMUST00000121820 ENSMUSP00000113115
ENSMUST00000138976
ENSMUST00000165024 ENSMUSP00000127155
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005539 glycosaminoglycan binding
GO:0050840 extracellular matrix binding
Biological Process
GO:0007165 signal transduction
GO:0010811 positive regulation of cell-substrate adhesion
GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
GO:0030198 extracellular matrix organization
Cellular Component
GO:0005578 proteinaceous extracellular matrix
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000107742
View Gene Order
ENSBTAG00000008827
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.153429 Mm.397505
RefSeq NM_052994 XM_006514347
OMIM
CCDS CCDS35910
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca