Version 5.4
Mus musculus Gene: Hecw2
Summary
InnateDB Gene IDBG-154418.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hecw2
Gene Name HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000042807
Encoded Proteins
IDBP-154420
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
IDBP-154422
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
IDBP-401340
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138411:
Gene Information
Type Protein coding
Genomic Location Chromosome 1:53806876-54195168
Strand Reverse strand
Band C1.1
Transcripts
ENSMUST00000087659 ENSMUSP00000084942
ENSMUST00000097741 ENSMUSP00000095348
ENSMUST00000120904 ENSMUSP00000113283
ENSMUST00000150677
ENSMUST00000152870
ENSMUST00000146850
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0016874 ligase activity
Biological Process
GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000138411
View Gene Order
Cross-References
SwissProt Q6I6G8
TrEMBL A3KPB7 Q8BQD5
UniProt Splice Variant
Entrez Gene 329152
UniGene Mm.132150 Mm.403683 Mm.447527
RefSeq NM_001001883 NM_172655 XM_006496066 XM_006496067 XM_006496068 XM_006496069
OMIM
CCDS CCDS14956 CCDS14957
HPRD
IMGT
MGI ID MGI:2685817
MGI Symbol Hecw2
EMBL AB182244 AK042922 AK050978 AK129325 BC107219 BC134353 CH466548
GenPept AAI07220 AAI34354 BAC31406 BAC34482 BAC98135 BAD23960 EDL00005
RNA Seq Atlas 329152

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca