Version 5.4
Mus musculus Gene: Pip5k1b
Summary
InnateDB Gene IDBG-154627.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pip5k1b
Gene Name phosphatidylinositol-4-phosphate 5-kinase, type 1 beta
Synonyms PI4P5K-I[b]; PIP5K1-beta; PIP5KIbeta; Pipk5b; STM7
Species Mus musculus
Ensembl Gene ENSMUSG00000024867
Encoded Proteins
IDBP-154629
phosphatidylinositol-4-phosphate 5-kinase, type 1 beta
IDBP-255519
phosphatidylinositol-4-phosphate 5-kinase, type 1 beta
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000107242:
Gene Information
Type Protein coding
Genomic Location Chromosome 19:24294794-24555872
Strand Reverse strand
Band B
Transcripts
ENSMUST00000025800 ENSMUSP00000025800
ENSMUST00000112673 ENSMUSP00000108292
ENSMUST00000134360
ENSMUST00000156814
ENSMUST00000145829
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016307 phosphatidylinositol phosphate kinase activity
GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity
Biological Process
GO:0046488 phosphatidylinositol metabolic process
GO:0046854 phosphatidylinositol phosphorylation
Cellular Component
GO:0001931 uropod
GO:0012505 endomembrane system
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000107242
View Gene Order
ENSBTAG00000009917
Not yet available
Pathways
NETPATH
REACTOME
REACT_198973
Synthesis of PIPs at the plasma membrane pathway
REACT_189085
Disease pathway
REACT_214014
Signaling by Wnt pathway
REACT_233046
Signaling by WNT in cancer pathway
REACT_199016
PI Metabolism pathway
REACT_188937
Metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_262115
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling pathway
REACT_241644
RNF mutants show enhanced WNT signaling and proliferation pathway
REACT_207044
TCF dependent signaling in response to WNT pathway
REACT_188643
Phospholipid metabolism pathway
REACT_188257
Signal Transduction pathway
REACT_225118
WNT mediated activation of DVL pathway
REACT_241402
XAV939 inhibits tankyrase, stabilizing AXIN pathway
KEGG
mmu04070
Phosphatidylinositol signaling system pathway
mmu04810
Regulation of actin cytoskeleton pathway
mmu00562
Inositol phosphate metabolism pathway
mmu04666
Fc gamma R-mediated phagocytosis pathway
mmu04144
Endocytosis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_8
Wnt pathway
NetPath_12
BCR pathway
REACTOME
REACT_121025
Synthesis of PIPs at the plasma membrane pathway
REACT_200668
WNT mediated activation of DVL pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_228096
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling pathway
REACT_228331
Signaling by WNT in cancer pathway
REACT_11045
Signaling by Wnt pathway
REACT_111102
Signal Transduction pathway
REACT_200777
TCF dependent signaling in response to WNT pathway
REACT_121175
PI Metabolism pathway
REACT_120870
Phospholipid metabolism pathway
REACT_228188
RNF mutants show enhanced WNT signaling and proliferation pathway
REACT_111217
Metabolism pathway
REACT_228279
XAV939 inhibits tankyrase, stabilizing AXIN pathway
REACT_116125
Disease pathway
KEGG
hsa04810
Regulation of actin cytoskeleton pathway
hsa00562
Inositol phosphate metabolism pathway
hsa04070
Phosphatidylinositol signaling system pathway
hsa04666
Fc gamma R-mediated phagocytosis pathway
hsa04144
Endocytosis pathway
INOH
INOH website
Inositol phosphate metabolism pathway
PID NCI
plexind1_pathway
Plexin-D1 Signaling
rac1_pathway
RAC1 signaling pathway
wnt_canonical_pathway
Canonical Wnt signaling pathway
Cross-References
SwissProt P70181
TrEMBL
UniProt Splice Variant
Entrez Gene 18719
UniGene
RefSeq NM_008846 XM_006526763
OMIM
CCDS CCDS37940
HPRD
IMGT
MGI ID MGI:107930
MGI Symbol Pip5k1b
EMBL AF048695 AK146100 AK149354 AK164552 BC034864 D86176
GenPept AAC05374 AAH34864 BAA13030 BAE26901 BAE28830 BAE37836
RNA Seq Atlas 18719

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca