Version 5.4
Mus musculus Gene: Snx4
Summary
InnateDB Gene IDBG-155276.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Snx4
Gene Name sorting nexin 4
Synonyms 1810036H14Rik; AI037066
Species Mus musculus
Ensembl Gene ENSMUSG00000022808
Encoded Proteins
IDBP-155278
sorting nexin 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000114520:
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor in cell cultures, but its function is unknown. This protein may form oligomeric complexes with family members. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:33251456-33299562
Strand Forward strand
Band B3
Transcripts
ENSMUST00000023502 ENSMUSP00000023502
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0035091 phosphatidylinositol binding
Biological Process
GO:0006886 intracellular protein transport
GO:0015031 protein transport
GO:0032456 endocytic recycling
Cellular Component
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005868 cytoplasmic dynein complex
GO:0031901 early endosome membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000114520
View Gene Order
ENSBTAG00000011383
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_7
TGF_beta_Receptor pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt Q91YJ2
TrEMBL Q80X54
UniProt Splice Variant
Entrez Gene 69150
UniGene Mm.407232
RefSeq NM_080557
OMIM
CCDS CCDS28129
HPRD
IMGT
MGI ID MGI:1916400
MGI Symbol Snx4
EMBL AK135356 BC016599 BC050851
GenPept AAH16599 AAH50851 BAE22501
RNA Seq Atlas 69150

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca