Mus musculus Gene: Atp6ap1 | |||||||||||||||||
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Summary | |||||||||||||||||
InnateDB Gene | IDBG-155785.6 | ||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||
Gene Symbol | Atp6ap1 | ||||||||||||||||
Gene Name | ATPase, H+ transporting, lysosomal accessory protein 1 | ||||||||||||||||
Synonyms | 16A; AC45; AI316502; Atp6ip1; Atp6s1; AW108110; C7-1; CF2; mFLJ00383; VATPS1; XAP-3 | ||||||||||||||||
Species | Mus musculus | ||||||||||||||||
Ensembl Gene | ENSMUSG00000019087 | ||||||||||||||||
Encoded Proteins |
ATPase, H+ transporting, lysosomal accessory protein 1
ATPase, H+ transporting, lysosomal accessory protein 1
ATPase, H+ transporting, lysosomal accessory protein 1
ATPase, H+ transporting, lysosomal accessory protein 1
ATPase, H+ transporting, lysosomal accessory protein 1
ATPase, H+ transporting, lysosomal accessory protein 1
ATPase, H+ transporting, lysosomal accessory protein 1
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Protein Structure | |||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||
Entrez Gene | |||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000071553:
This gene encodes a component of a multisubunit enzyme (1 mDa MW) that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene is approximately 45 kD and may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules. [provided by RefSeq, Jul 2008] This gene encodes a component of a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules. This protein may also play a role in early development. [provided by RefSeq, Aug 2013] |
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Gene Information | |||||||||||||||||
Type | Protein coding | ||||||||||||||||
Genomic Location | Chromosome X:74297097-74304721 | ||||||||||||||||
Strand | Forward strand | ||||||||||||||||
Band | A7.3 | ||||||||||||||||
Transcripts | |||||||||||||||||
Interactions | |||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||
NETPATH | |||||||||||||||||
REACTOME |
Signaling by Insulin receptor pathway
Transferrin endocytosis and recycling pathway
Iron uptake and transport pathway
Transmembrane transport of small molecules pathway
Insulin receptor recycling pathway
Signal Transduction pathway
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KEGG |
Oxidative phosphorylation pathway
Lysosome pathway
Phagosome pathway
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INOH | |||||||||||||||||
PID NCI | |||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||
NETPATH | |||||||||||||||||
REACTOME |
Transferrin endocytosis and recycling pathway
Iron uptake and transport pathway
Insulin receptor recycling pathway
Signaling by Insulin receptor pathway
Transmembrane transport of small molecules pathway
Signal Transduction pathway
Transferrin endocytosis and recycling pathway
Iron uptake and transport pathway
Transmembrane transport of small molecules pathway
Signal Transduction pathway
Signaling by Insulin receptor pathway
Insulin receptor recycling pathway
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KEGG |
Vibrio cholerae infection pathway
Epithelial cell signaling in Helicobacter pylori infection pathway
Oxidative phosphorylation pathway
Lysosome pathway
Phagosome pathway
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INOH | |||||||||||||||||
PID NCI | |||||||||||||||||
Cross-References | |||||||||||||||||
SwissProt | |||||||||||||||||
TrEMBL | |||||||||||||||||
UniProt Splice Variant | |||||||||||||||||
Entrez Gene | |||||||||||||||||
UniGene | Mm.21961 Mm.489665 | ||||||||||||||||
RefSeq | NM_018794 | ||||||||||||||||
OMIM | |||||||||||||||||
CCDS | CCDS30226 | ||||||||||||||||
HPRD | |||||||||||||||||
IMGT | |||||||||||||||||
MGI ID | |||||||||||||||||
MGI Symbol | |||||||||||||||||
EMBL | |||||||||||||||||
GenPept | |||||||||||||||||
RNA Seq Atlas | |||||||||||||||||