Version 5.4
| Mus musculus Gene: Pdlim7 | |||||||||||||||||||||||
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| Summary | |||||||||||||||||||||||
| InnateDB Gene | IDBG-156136.6 | ||||||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
| Gene Symbol | Pdlim7 | ||||||||||||||||||||||
| Gene Name | PDZ and LIM domain 7 | ||||||||||||||||||||||
| Synonyms | LMP | ||||||||||||||||||||||
| Species | Mus musculus | ||||||||||||||||||||||
| Ensembl Gene | ENSMUSG00000021493 | ||||||||||||||||||||||
| Encoded Proteins |
PDZ and LIM domain 7
PDZ and LIM domain 7
PDZ and LIM domain 7
PDZ and LIM domain 7
PDZ and LIM domain 7
PDZ and LIM domain 7
PDZ and LIM domain 7
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
| Entrez Gene | |||||||||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000196923:
The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||||||
| Genomic Location | Chromosome 13:55495795-55513676 | ||||||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||||||
| Band | B1 | ||||||||||||||||||||||
| Transcripts | |||||||||||||||||||||||
| Interactions | |||||||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 32 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
| NETPATH | |||||||||||||||||||||||
| REACTOME | |||||||||||||||||||||||
| KEGG | |||||||||||||||||||||||
| INOH | |||||||||||||||||||||||
| PID NCI |
Signaling events regulated by Ret tyrosine kinase
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| Cross-References | |||||||||||||||||||||||
| SwissProt | Q3TJD7 | ||||||||||||||||||||||
| TrEMBL | B8JJB1 B8JJB2 | ||||||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||||||
| Entrez Gene | 67399 | ||||||||||||||||||||||
| UniGene | |||||||||||||||||||||||
| RefSeq | NM_001114087 NM_001114088 NM_026131 XM_006517345 XM_006517347 XM_006517348 | ||||||||||||||||||||||
| OMIM | |||||||||||||||||||||||
| CCDS | CCDS49275 CCDS26547 CCDS49276 | ||||||||||||||||||||||
| HPRD | |||||||||||||||||||||||
| IMGT | |||||||||||||||||||||||
| MGI ID | MGI:1914649 | ||||||||||||||||||||||
| MGI Symbol | Pdlim7 | ||||||||||||||||||||||
| EMBL | AK003019 AK003338 AK010141 AK167476 BC045528 BC049565 CT009762 | ||||||||||||||||||||||
| GenPept | AAH45528 AAH49565 BAB22725 BAB26726 BAC25017 BAE39558 | ||||||||||||||||||||||
| RNA Seq Atlas | 67399 | ||||||||||||||||||||||