Version 5.4
Mus musculus Gene: Crat
Summary
InnateDB Gene IDBG-156667.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Crat
Gene Name carnitine acetyltransferase
Synonyms AW107812; CARAT
Species Mus musculus
Ensembl Gene ENSMUSG00000026853
Encoded Proteins
IDBP-156669
carnitine acetyltransferase
IDBP-156671
carnitine acetyltransferase
IDBP-156673
carnitine acetyltransferase
IDBP-536414
carnitine acetyltransferase
IDBP-541605
carnitine acetyltransferase
IDBP-532203
carnitine acetyltransferase
IDBP-536569
carnitine acetyltransferase
IDBP-536012
carnitine acetyltransferase
IDBP-535106
carnitine acetyltransferase
IDBP-535287
carnitine acetyltransferase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000095321:
This gene encodes carnitine acetyltransferase (CRAT), which is a key enzyme in the metabolic pathway in mitochondria, peroxisomes and endoplasmic reticulum. CRAT catalyzes the reversible transfer of acyl groups from an acyl-CoA thioester to carnitine and regulates the ratio of acylCoA/CoA in the subcellular compartments. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:30400471-30415813
Strand Reverse strand
Band B
Transcripts
ENSMUST00000102855 ENSMUSP00000099919
ENSMUST00000028207 ENSMUSP00000028207
ENSMUST00000102854 ENSMUSP00000099918
ENSMUST00000146603
ENSMUST00000155790 ENSMUSP00000122814
ENSMUST00000154595 ENSMUSP00000114925
ENSMUST00000156702 ENSMUSP00000117317
ENSMUST00000132981 ENSMUSP00000118507
ENSMUST00000146822
ENSMUST00000134120 ENSMUSP00000117593
ENSMUST00000129494 ENSMUSP00000122025
ENSMUST00000128593
ENSMUST00000142096 ENSMUSP00000119735
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004092 carnitine O-acetyltransferase activity
GO:0005102 receptor binding
GO:0016746 transferase activity, transferring acyl groups
Biological Process
GO:0006631 fatty acid metabolic process
GO:0006810 transport
GO:0008152 metabolic process
GO:0019254 carnitine metabolic process, CoA-linked
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005777 peroxisome
GO:0005783 endoplasmic reticulum
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000095321
View Gene Order
ENSBTAG00000001932
Not yet available
Pathways
NETPATH
REACTOME
REACT_188937
Metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_247416
Beta-oxidation of very long chain fatty acids pathway
REACT_243096
Beta-oxidation of pristanoyl-CoA pathway
REACT_246750
Peroxisomal lipid metabolism pathway
KEGG
mmu04146
Peroxisome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_17062
Beta-oxidation of very long chain fatty acids pathway
REACT_17017
Beta-oxidation of pristanoyl-CoA pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_16957
Peroxisomal lipid metabolism pathway
REACT_111217
Metabolism pathway
KEGG
hsa04146
Peroxisome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.20396
RefSeq NM_007760 XM_006497645 XM_006497646 XM_006497647 XM_006497648
OMIM
CCDS CCDS15882
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca