Version 5.4
Homo sapiens Gene: BRPF1
Summary
InnateDB Gene IDBG-15675.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BRPF1
Gene Name bromodomain and PHD finger containing, 1
Synonyms BR140
Species Homo sapiens
Ensembl Gene ENSG00000156983
Encoded Proteins
IDBP-15679
bromodomain and PHD finger containing, 1
IDBP-361665
bromodomain and PHD finger containing, 1
IDBP-361668
bromodomain and PHD finger containing, 1
IDBP-361671
bromodomain and PHD finger containing, 1
IDBP-361672
bromodomain and PHD finger containing, 1
IDBP-361673
bromodomain and PHD finger containing, 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is expressed ubiquitously and at the highest level in testes and spermatogonia. The protein is localized within nuclei, and it is very similar in structure to two zinc finger proteins, AF10 and AF17. It is suggested that these proteins form a family of regulatory proteins. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:9731729-9748018
Strand Forward strand
Band p25.3
Transcripts
ENST00000383829 ENSP00000373340
ENST00000424362 ENSP00000398863
ENST00000433861 ENSP00000402485
ENST00000420291 ENSP00000416728
ENST00000426583 ENSP00000404235
ENST00000457855 ENSP00000410210
ENST00000469066
ENST00000497565
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006325 chromatin organization
GO:0006351 transcription, DNA-templated
GO:0043966 histone H3 acetylation
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0070776 MOZ/MORF histone acetyltransferase complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000001632
View Gene Order
ENSBTAG00000007776
Not yet available
Pathways
NETPATH
REACTOME
REACT_172610
HATs acetylate histones pathway
REACT_172623
Chromatin organization pathway
REACT_172633
Chromatin modifying enzymes pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.1004
RefSeq NM_001003694 NM_004634 XM_005265450 XM_005265451 XM_005265452 XM_005265453 XM_005265454
HUGO
OMIM
CCDS CCDS2575 CCDS33692
HPRD 03875
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca