Version 5.4
Mus musculus Gene: Ltbp2
Summary
InnateDB Gene IDBG-157147.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ltbp2
Gene Name latent transforming growth factor beta binding protein 2
Synonyms AW208642
Species Mus musculus
Ensembl Gene ENSMUSG00000002020
Encoded Proteins
IDBP-157149
latent transforming growth factor beta binding protein 2
IDBP-260650
latent transforming growth factor beta binding protein 2
IDBP-621189
latent transforming growth factor beta binding protein 2
IDBP-621190
latent transforming growth factor beta binding protein 2
IDBP-621191
latent transforming growth factor beta binding protein 2
IDBP-621193
latent transforming growth factor beta binding protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000119681:
The protein encoded by this gene belongs to the family of latent transforming growth factor (TGF)-beta binding proteins (LTBP), which are extracellular matrix proteins with multi-domain structure. This protein is the largest member of the LTBP family possessing unique regions and with most similarity to the fibrillins. It has thus been suggested that it may have multiple functions: as a member of the TGF-beta latent complex, as a structural component of microfibrils, and a role in cell adhesion. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:84783212-84876532
Strand Reverse strand
Band D1
Transcripts
ENSMUST00000002073 ENSMUSP00000002073
ENSMUST00000110254 ENSMUSP00000105883
ENSMUST00000163189 ENSMUSP00000127693
ENSMUST00000166383 ENSMUSP00000127255
ENSMUST00000163214 ENSMUSP00000132067
ENSMUST00000165141 ENSMUSP00000132690
ENSMUST00000168699
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005615 extracellular space
GO:0031012 extracellular matrix
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000119681
View Gene Order
ENSBTAG00000021957
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_150331
Molecules associated with elastic fibres pathway
REACT_150366
Elastic fibre formation pathway
REACT_118779
Extracellular matrix organization pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 16997
UniGene Mm.3900
RefSeq NM_013589 XM_006515501
OMIM
CCDS CCDS49112
HPRD
IMGT
MGI ID MGI:99502
MGI Symbol Ltbp2
EMBL
GenPept
RNA Seq Atlas 16997

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca