Mus musculus Gene: A1cf | |||||||||||
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Summary | |||||||||||
InnateDB Gene | IDBG-158361.6 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | A1cf | ||||||||||
Gene Name | APOBEC1 complementation factor | ||||||||||
Synonyms | 1810073H04Rik; Acf; ACF64; ACF65; ASP | ||||||||||
Species | Mus musculus | ||||||||||
Ensembl Gene | ENSMUSG00000052595 | ||||||||||
Encoded Proteins |
APOBEC1 complementation factor
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Protein Structure | |||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
Entrez Gene | |||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000148584:
Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010] |
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Gene Information | |||||||||||
Type | Protein coding | ||||||||||
Genomic Location | Chromosome 19:31868761-31949406 | ||||||||||
Strand | Forward strand | ||||||||||
Band | C1 | ||||||||||
Transcripts |
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Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||
NETPATH | |||||||||||
REACTOME |
Formation of the Editosome pathway
mRNA Editing: C to U Conversion pathway
Gene Expression pathway
mRNA Editing pathway
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KEGG | |||||||||||
INOH | |||||||||||
PID NCI | |||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||
NETPATH | |||||||||||
REACTOME |
Formation of the Editosome pathway
mRNA Editing: C to U Conversion pathway
mRNA Editing pathway
Gene Expression pathway
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KEGG | |||||||||||
INOH | |||||||||||
PID NCI | |||||||||||
Cross-References | |||||||||||
SwissProt | |||||||||||
TrEMBL | |||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | |||||||||||
UniGene | Mm.87538 | ||||||||||
RefSeq | NM_001081074 XM_006527332 | ||||||||||
OMIM | |||||||||||
CCDS | CCDS37959 | ||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
MGI ID | |||||||||||
MGI Symbol | |||||||||||
EMBL | |||||||||||
GenPept | |||||||||||
RNA Seq Atlas | |||||||||||