Version 5.4
| Mus musculus Gene: Ctif | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-158912.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | Ctif | ||||||||||||||||||
| Gene Name | CBP80/20-dependent translation initiation factor | ||||||||||||||||||
| Synonyms | |||||||||||||||||||
| Species | Mus musculus | ||||||||||||||||||
| Ensembl Gene | ENSMUSG00000052928 | ||||||||||||||||||
| Encoded Proteins |
CBP80/20-dependent translation initiation factor
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| Protein Structure | |||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134030:
CTIF is a component of the CBP80 (NCBP1; MIM 600469)/CBP20 (NCBP2; MIM 605133) translation initiation complex that binds cotranscriptionally to the cap end of nascent mRNA. The CBP80/CBP20 complex is involved in a simultaneous editing and translation step that recognizes premature termination codons (PTCs) in mRNAs and directs PTC-containing mRNAs toward nonsense-mediated decay (NMD). On mRNAs without PTCs, the CBP80/CBP20 complex is replaced with cytoplasmic mRNA cap-binding proteins, including EIF4G (MIM 600495), and steady-state translation of the mRNAs resumes in the cytoplasm (Kim et al., 2009 [PubMed 19648179]).[supplied by OMIM, Dec 2009] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 18:75431224-75697696 | ||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||
| Band | E3 | ||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Cross-References | |||||||||||||||||||
| SwissProt | |||||||||||||||||||
| TrEMBL | E9Q1U6 | ||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 269037 | ||||||||||||||||||
| UniGene | Mm.36745 Mm.409733 Mm.418094 Mm.420836 Mm.429797 | ||||||||||||||||||
| RefSeq | NM_201354 XM_006525967 XM_006525968 XM_006525969 XM_006525970 XM_006525971 XM_006525972 | ||||||||||||||||||
| OMIM | |||||||||||||||||||
| CCDS | CCDS37861 | ||||||||||||||||||
| HPRD | |||||||||||||||||||
| IMGT | |||||||||||||||||||
| MGI ID | MGI:2685518 | ||||||||||||||||||
| MGI Symbol | Ctif | ||||||||||||||||||
| EMBL | AC113528 AC120156 AC120176 | ||||||||||||||||||
| GenPept | |||||||||||||||||||
| RNA Seq Atlas | 269037 | ||||||||||||||||||