Version 5.4
Mus musculus Gene: Mrpl24
Summary
InnateDB Gene IDBG-159024.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mrpl24
Gene Name mitochondrial ribosomal protein L24
Synonyms 2010005E08Rik; 2810470K06Rik; 6720473G22Rik; AA407670
Species Mus musculus
Ensembl Gene ENSMUSG00000019710
Encoded Proteins
IDBP-159026
mitochondrial ribosomal protein L24
IDBP-401194
mitochondrial ribosomal protein L24
IDBP-401193
mitochondrial ribosomal protein L24
IDBP-401192
mitochondrial ribosomal protein L24
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143314:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which is more than twice the size of its E.coli counterpart (EcoL24). Sequence analysis identified two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:87919506-87923672
Strand Forward strand
Band F1
Transcripts
ENSMUST00000019854 ENSMUSP00000019854
ENSMUST00000119968 ENSMUSP00000114111
ENSMUST00000121920 ENSMUSP00000112885
ENSMUST00000121048 ENSMUSP00000113959
ENSMUST00000137775
ENSMUST00000152287
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.
Predicted by orthology
Total 26 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005622 intracellular
GO:0005739 mitochondrion
GO:0005840 ribosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000143314
View Gene Order
ENSBTAG00000001520
Not yet available
Pathways
NETPATH
REACTOME
REACT_268789
Mitochondrial translation pathway
REACT_224594
Organelle biogenesis and maintenance pathway
REACT_270125
Mitochondrial translation elongation pathway
REACT_271096
Mitochondrial translation initiation pathway
REACT_270158
Mitochondrial translation termination pathway
KEGG
mmu03010
Ribosome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_200751
Organelle biogenesis and maintenance pathway
REACT_267673
Mitochondrial translation pathway
REACT_267680
Mitochondrial translation initiation pathway
REACT_267602
Mitochondrial translation termination pathway
REACT_267677
Mitochondrial translation elongation pathway
REACT_270797
Mitochondrial translation initiation pathway
REACT_271447
Mitochondrial translation elongation pathway
REACT_270450
Mitochondrial translation pathway
REACT_270960
Mitochondrial translation termination pathway
REACT_219259
Organelle biogenesis and maintenance pathway
KEGG
hsa03010
Ribosome pathway
INOH
PID NCI
Cross-References
SwissProt Q9CQ06
TrEMBL
UniProt Splice Variant
Entrez Gene 67707
UniGene Mm.393802
RefSeq NM_026591 XM_006501942
OMIM
CCDS CCDS38477
HPRD
IMGT
MGI ID MGI:1914957
MGI Symbol Mrpl24
EMBL AK003362 AK008117 AK008961 AK013394 AK019976 AK020157 AK167623 BC004736 BC025506 BC031730
GenPept AAH04736 AAH25506 AAH31730 BAB22737 BAB25472 BAB25991 BAB28828 BAB31945 BAB32014 BAE39675
RNA Seq Atlas 67707

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca