Version 5.4
Mus musculus Gene: Isca1
Summary
InnateDB Gene IDBG-159082.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Isca1
Gene Name iron-sulfur cluster assembly 1 homolog (S. cerevisiae)
Synonyms 1810010A06Rik; Hbld2
Species Mus musculus
Ensembl Gene ENSMUSG00000044792
Encoded Proteins
IDBP-159084
iron-sulfur cluster assembly 1 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135070:
ISCA1 is a mitochondrial protein involved in the biogenesis and assembly of iron-sulfur clusters, which play a role in electron-transfer reactions (Cozar-Castellano et al., 2004 [PubMed 15262227]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:59755409-59769810
Strand Reverse strand
Band B2
Transcripts
ENSMUST00000057115 ENSMUSP00000054858
ENSMUST00000160628
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005198 structural molecule activity
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
Biological Process
GO:0008150 biological_process
GO:0016226 iron-sulfur cluster assembly
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000135070
View Gene Order
ENSBTAG00000046526
Not yet available
Cross-References
SwissProt Q9D924
TrEMBL
UniProt Splice Variant
Entrez Gene 69046
UniGene Mm.399408 Mm.471937
RefSeq NM_026921
OMIM
CCDS CCDS26578
HPRD
IMGT
MGI ID MGI:1916296
MGI Symbol Isca1
EMBL AC134869 AK007415 AK045175 AK090000 AK153820 AK169028 BC018547 BC085482
GenPept AAH18547 AAH85482 BAB25025 BAC32248 BAC41037 BAE32196 BAE40820
RNA Seq Atlas 69046

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca