Version 5.4
Mus musculus Gene: Ints10
Summary
InnateDB Gene IDBG-159402.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ints10
Gene Name integrator complex subunit 10
Synonyms 4921521J11Rik; AI462004
Species Mus musculus
Ensembl Gene ENSMUSG00000031864
Encoded Proteins
IDBP-159404
integrator complex subunit 10
IDBP-159406
integrator complex subunit 10
IDBP-260688
integrator complex subunit 10
IDBP-260690
integrator complex subunit 10
IDBP-535376
integrator complex subunit 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000104613:
INTS10 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:68793929-68829410
Strand Forward strand
Band B3.3
Transcripts
ENSMUST00000034328 ENSMUSP00000034328
ENSMUST00000070713 ENSMUSP00000069908
ENSMUST00000110242 ENSMUSP00000105871
ENSMUST00000110241 ENSMUSP00000105870
ENSMUST00000146322
ENSMUST00000145140
ENSMUST00000140309
ENSMUST00000147072 ENSMUSP00000118390
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0016180 snRNA processing
Cellular Component
GO:0005737 cytoplasm
GO:0032039 integrator complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000104613
View Gene Order
ENSBTAG00000025003
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.252421 Mm.474073
RefSeq NM_027590 XM_006509743 XM_006509744 XM_006509745 XM_006509746 XM_006509747
OMIM
CCDS CCDS22342
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca