Mus musculus Gene: Fxyd6 | |||||||
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Summary | |||||||
InnateDB Gene | IDBG-159611.6 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | Fxyd6 | ||||||
Gene Name | FXYD domain-containing ion transport regulator 6 | ||||||
Synonyms | 0610030I18Rik; Php | ||||||
Species | Mus musculus | ||||||
Ensembl Gene | ENSMUSG00000066705 | ||||||
Encoded Proteins |
FXYD domain-containing ion transport regulator 6
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Protein Structure | |||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||
Entrez Gene | |||||||
Summary |
This reference sequence was derived from multiple replicate ESTs and validated by similar human genomic sequence. This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. This gene product, Fxyd6, is novel and has not been characterized as a protein. [RefSeq curation by Kathleen J. Sweadner, Ph.D., sweadner@helix.mgh.harvard.edu., Jul 2006] |
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Gene Information | |||||||
Type | Protein coding | ||||||
Genomic Location | Chromosome 9:45370185-45396158 | ||||||
Strand | Forward strand | ||||||
Band | A5.2 | ||||||
Transcripts |
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Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||
NETPATH | |||||||
REACTOME |
Ion channel transport pathway
Transmembrane transport of small molecules pathway
Ion transport by P-type ATPases pathway
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KEGG | |||||||
INOH | |||||||
PID NCI | |||||||
Pathway Predictions based on Human Orthology Data | |||||||
NETPATH | |||||||
REACTOME |
Ion transport by P-type ATPases pathway
Transmembrane transport of small molecules pathway
Ion channel transport pathway
Ion channel transport pathway
Transmembrane transport of small molecules pathway
Ion transport by P-type ATPases pathway
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KEGG | |||||||
INOH | |||||||
PID NCI | |||||||
Cross-References | |||||||
SwissProt | Q9D164 | ||||||
TrEMBL | |||||||
UniProt Splice Variant | |||||||
Entrez Gene | 59095 | ||||||
UniGene | Mm.474649 | ||||||
RefSeq | NM_022004 XM_006510521 XM_006510522 | ||||||
OMIM | |||||||
CCDS | CCDS23133 | ||||||
HPRD | |||||||
IMGT | |||||||
MGI ID | MGI:1890226 | ||||||
MGI Symbol | Fxyd6 | ||||||
EMBL | AB032010 AK003888 AK018354 BC042579 BC051127 | ||||||
GenPept | AAH42579 AAH51127 BAB23058 BAB31174 BAB40451 | ||||||
RNA Seq Atlas | 59095 | ||||||