InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Ndufb4

Summary

InnateDB Gene

IDBG-159659.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ndufb4

Gene Name

NADH dehydrogenase (ubiquinone) 1 beta subcomplex 4

Synonyms

0610006N12Rik; 1300010H20Rik

Species

Mus musculus

Ensembl Gene

ENSMUSG00000022820

Encoded Proteins

IDBP-159661

NADH dehydrogenase (ubiquinone) 1 beta subcomplex 4

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000065518:
This gene encodes a non-catalytic subunit of the multisubunit NADH:ubiquinone oxidoreductase, the first enzyme complex in the mitochondrial electron transport chain (complex I). Mammalian complex I is composed of 45 different subunits and transfers electrons from NADH to ubiquinone. [provided by RefSeq, Dec 2009]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 16:37647170-37654453

Strand

Reverse strand

Band

Transcripts

ENSMUST00000023514	ENSMUSP00000023514
ENSMUST00000135019

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008137	NADH dehydrogenase (ubiquinone) activity

Biological Process

GO:0006979	response to oxidative stress
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005634	nucleus
GO:0005739	mitochondrion
GO:0005747	mitochondrial respiratory chain complex I
GO:0016021	integral component of membrane
GO:0031965	nuclear membrane
GO:0070062	extracellular vesicular exosome