Version 5.4
Mus musculus Gene: Sh3bp1
Summary
InnateDB Gene IDBG-160157.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sh3bp1
Gene Name SH3-domain binding protein 1
Synonyms 1600027H05Rik; 3BP-1; AB041662; PLPP
Species Mus musculus
Ensembl Gene ENSMUSG00000022436
Encoded Proteins
IDBP-160159
SH3-domain binding protein 1
IDBP-160161
SH3-domain binding protein 1
IDBP-261840
SH3-domain binding protein 1
IDBP-789754
SH3-domain binding protein 1
IDBP-789755
SH3-domain binding protein 1
IDBP-536199
SH3-domain binding protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100092:
Gene Information
Type Protein coding
Genomic Location Chromosome 15:78899667-78919517
Strand Forward strand
Band E1
Transcripts
ENSMUST00000061239 ENSMUSP00000052181
ENSMUST00000001226 ENSMUSP00000001226
ENSMUST00000109698 ENSMUSP00000105320
ENSMUST00000134703
ENSMUST00000151146 ENSMUSP00000138780
ENSMUST00000132047 ENSMUSP00000138598
ENSMUST00000148893 ENSMUSP00000117839
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0004647 phosphoserine phosphatase activity
GO:0004721 phosphoprotein phosphatase activity
GO:0005515 protein binding
GO:0016791 phosphatase activity
GO:0017124 SH3 domain binding
GO:0031072 heat shock protein binding
GO:0033883 pyridoxal phosphatase activity
GO:0042803 protein homodimerization activity
Biological Process
GO:0006470 protein dephosphorylation
GO:0007088 regulation of mitosis
GO:0007165 signal transduction
GO:0008152 metabolic process
GO:0030836 positive regulation of actin filament depolymerization
GO:0031247 actin rod assembly
GO:0032361 pyridoxal phosphate catabolic process
GO:0032465 regulation of cytokinesis
GO:0071318 cellular response to ATP
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0015629 actin cytoskeleton
GO:0030027 lamellipodium
GO:0030496 midbody
GO:0031258 lamellipodium membrane
GO:0032154 cleavage furrow
GO:0032587 ruffle membrane
GO:0070938 contractile ring
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000100092
View Gene Order
ENSBTAG00000030257
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00750
Vitamin B6 metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.4462 Mm.486751
RefSeq NM_009164 NM_020271 XM_006520661
OMIM
CCDS CCDS27626 CCDS27627
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca