Mus musculus Gene: Slc7a7
Summary
InnateDB Gene IDBG-161063.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc7a7
Gene Name solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
Synonyms AI790233; my+lat1;
Species Mus musculus
Ensembl Gene ENSMUSG00000000958
Encoded Proteins
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000155465:
The protein encoded by this gene is the light subunit of a cationic amino acid transporter. This sodium-independent transporter is formed when the light subunit encoded by this gene dimerizes with the heavy subunit transporter protein SLC3A2. This transporter is found in epithelial cell membranes where it transfers cationic and large neutral amino acids from the cell to the extracellular space. Defects in this gene are a cause of lysinuric protein intolerance (LPI). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:54369444-54409472
Strand Reverse strand
Band C2
Transcripts
ENSMUST00000000984 ENSMUSP00000000984
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0015171 amino acid transmembrane transporter activity
Biological Process
GO:0003333 amino acid transmembrane transport
GO:0006810 transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Hemostasis pathway
SLC-mediated transmembrane transport pathway
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
Cell surface interactions at the vascular wall pathway
Basigin interactions pathway
Transmembrane transport of small molecules pathway
Amino acid transport across the plasma membrane pathway
KEGG
Protein digestion and absorption pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Transmembrane transport of small molecules pathway
Amino acid transport across the plasma membrane pathway
Basigin interactions pathway
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
SLC-mediated transmembrane transport pathway
Cell surface interactions at the vascular wall pathway
Hemostasis pathway
KEGG
Protein digestion and absorption pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q9Z1K8
TrEMBL
UniProt Splice Variant
Entrez Gene 20540
UniGene
RefSeq NM_001253679 NM_001253680 NM_011405 XM_006518745 XM_006518746 XM_006518747 XM_006518748 XM_006518749 XM_006518750 XM_006518751 XM_006518752 XM_006518753 XM_006518754 XM_006518755
OMIM
CCDS CCDS27087
HPRD
IMGT
MGI ID MGI:1337120
MGI Symbol Slc7a7
EMBL AJ012754 AJ130943 AK150950 AK151718 AK152637 AK170851 BC014709
GenPept AAH14709 BAE29983 BAE30637 BAE31379 BAE42073 CAA10170 CAA10255
RNA Seq Atlas 20540