Mus musculus Gene: Zwint
Summary
InnateDB Gene IDBG-161923.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Zwint
Gene Name ZW10 interactor
Synonyms 2010007E07Rik; 2600001N01Rik; D10Ertd749e; Zwint-1;
Species Mus musculus
Ensembl Gene ENSMUSG00000019923
Encoded Proteins
ZW10 interactor
ZW10 interactor
ZW10 interactor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000122952:
This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:72654845-72674964
Strand Forward strand
Band B5.3
Transcripts
ENSMUST00000020081 ENSMUSP00000020081
ENSMUST00000105431 ENSMUSP00000101071
ENSMUST00000160337 ENSMUSP00000124429
ENSMUST00000160128
ENSMUST00000163046
ENSMUST00000159549
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 38 interaction(s) predicted by orthology.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 38 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0047485 protein N-terminus binding
Biological Process
GO:0000070 mitotic sister chromatid segregation
GO:0007093 mitotic cell cycle checkpoint
GO:0051649 establishment of localization in cell
Cellular Component
GO:0000777 condensed chromosome kinetochore
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0030425 dendrite
GO:0043005 neuron projection
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Cell Cycle, Mitotic pathway
Separation of Sister Chromatids pathway
Resolution of Sister Chromatid Cohesion pathway
Cell Cycle pathway
M Phase pathway
Mitotic Metaphase and Anaphase pathway
Mitotic Prometaphase pathway
Mitotic Anaphase pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Separation of Sister Chromatids pathway
Mitotic Prometaphase pathway
Cell Cycle pathway
M Phase pathway
Mitotic Anaphase pathway
Cell Cycle, Mitotic pathway
Resolution of Sister Chromatid Cohesion pathway
Mitotic Metaphase and Anaphase pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.413114 Mm.447758 Mm.62876
RefSeq NM_025635 XM_006513884 XM_006513885
OMIM
CCDS CCDS23920
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas