Version 5.4
Mus musculus Gene: Awat2
Summary
InnateDB Gene IDBG-161978.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Awat2
Gene Name acyl-CoA wax alcohol acyltransferase 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000031220
Encoded Proteins
IDBP-161980
acyl-CoA wax alcohol acyltransferase 2
IDBP-621771
acyl-CoA wax alcohol acyltransferase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000147160:
This gene encodes an enzyme belonging to the diacylglycerol acyltransferase family. This enzyme produces wax esters by the esterification of long chain (or wax) alcohols with acyl-CoA-derived fatty acids. It functions in lipid metabolism in the skin, mostly in undifferentiated peripheral sebocytes. This enzyme may also have acyl-CoA:retinol acyltransferase activities, where it catalyzes the synthesis of diacylglycerols and retinyl esters. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:100402221-100442717
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000033567 ENSMUSP00000033567
ENSMUST00000147103 ENSMUSP00000128516
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups
GO:0047196 long-chain-alcohol O-fatty-acyltransferase activity
GO:0050252 retinol O-fatty-acyltransferase activity
Biological Process
GO:0010025 wax biosynthetic process
GO:0042572 retinol metabolic process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000147160
View Gene Order
ENSBTAG00000012281
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00830
Retinol metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00830
Retinol metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.118171
RefSeq NM_001290395 NM_177746 XM_006528028
OMIM
CCDS CCDS30300 CCDS72412
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca