Homo sapiens Gene: THOP1
Summary
InnateDB Gene IDBG-16324.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol THOP1
Gene Name thimet oligopeptidase 1
Synonyms EP24.15; MEPD_HUMAN; MP78; TOP;
Species Homo sapiens
Ensembl Gene ENSG00000172009
Encoded Proteins
thimet oligopeptidase 1
thimet oligopeptidase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:2785460-2815807
Strand Forward strand
Band p13.3
Transcripts
ENST00000307741 ENSP00000304467
ENST00000395212 ENSP00000378638
ENST00000589087
ENST00000590970 ENSP00000465855
ENST00000587401 ENSP00000465895
ENST00000592639
ENST00000590533
ENST00000586677 ENSP00000467226
ENST00000585338 ENSP00000465545
ENST00000587468 ENSP00000464786
ENST00000586780
ENST00000585673
ENST00000591149
ENST00000591363 ENSP00000466653
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 36 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 36 [view]
Protein-Protein 36 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0005515 protein binding
GO:0008233 peptidase activity
GO:0042277 peptide binding
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
GO:0006518 peptide metabolic process
GO:0035556 intracellular signal transduction
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
Renin-angiotensin system pathway
African trypanosomiasis pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL K7EIK4
UniProt Splice Variant
Entrez Gene 7064
UniGene Hs.78769
RefSeq NM_003249
HUGO HGNC:11793
OMIM 601117
CCDS CCDS12095
HPRD 03072
IMGT
EMBL AC006538
GenPept
RNA Seq Atlas 7064